Long-QT Syndrome

被引：36

作者：

Kramer, Daniel B. ^{[1
]}

Zimetbaum, Peter J. ^{[1
]}

机构：

[1] Harvard Univ, Beth Israel Deaconess Med Ctr, Div Cardiovasc, Sch Med,Dept Med, Boston, MA 02215 USA

来源：

CARDIOLOGY IN REVIEW | 2011年 / 19卷 / 05期

关键词：

long QT syndrome; sudden cardiac death; GENOTYPE-PHENOTYPE CORRELATION; TORSADE-DE-POINTES; CARDIAC-ARRHYTHMIAS; MENSTRUAL-CYCLE; MOLECULAR-BASIS; LQT2; FORMS; HEART-RATE; EXERCISE; INTERVAL; RISK;

D O I：

10.1097/CRD.0b013e3182203504

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Acquired and hereditary long-QT syndromes are important causes of sudden cardiac death. Both categories are characterized by abnormally prolonged cardiac repolarization arising from a complex interaction between genetic and environmental factors. This produces a potentially dangerous substrate for polymorphic ventricular tachycardia and sudden cardiac death. In this review, the pathophysiologic, diagnostic, and prognostic features of long-QT syndromes, as well as recommendations regarding therapy, are reviewed.

引用

页码：217 / 225

页数：9

共 50 条

[31] When and where does the reentry Start in Long-QT syndrome?-A computer simulation study [J].

Jin Yinbin ;

Zhang Hong ;

Yang Lin ;

Yang Zhao .

2009 3RD INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICAL ENGINEERING, VOLS 1-11, 2009, :173-+

[32] Contribution of Long-QT Syndrome Genetic Variants in Sudden Infant Death Syndrome [J].

Millat, Gilles ;

Kugener, Beatrice ;

Chevalier, Philippe ;

Chahine, Mohamed ;

Huang, Hai ;

Malicier, Daniel ;

Rodriguez-Lafrasse, Claire ;

Rousson, Robert .

PEDIATRIC CARDIOLOGY, 2009, 30 (04) :502-509

[33] Congenital Long-QT Syndrome Concealed by Hypercalcemia in Williams Syndrome [J].

Czosek, Richard J. ;

Berul, Charles I. .

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 2008, 19 (12) :1322-1324

[34] Genotype-specific QT correction for heart rate and the risk of life-threatening cardiac events in adolescents with congenital long-QT syndrome [J].

Barsheshet, Alon ;

Peterson, Derick R. ;

Moss, Arthur J. ;

Schwartz, Peter J. ;

Kaufman, Elizabeth S. ;

McNitt, Scott ;

Polonsky, Slava ;

Buber, Jonathan ;

Zareba, Wojciech ;

Robinson, Jennifer L. ;

Ackerman, Michael J. ;

Benhorin, Jesaia ;

Towbin, Jeffrey A. ;

Vincent, G. Michael ;

Zhang, Li ;

Goldenberg, Ilan .

HEART RHYTHM, 2011, 8 (08) :1207-1213

[35] Ranolazine for Congenital Long-QT Syndrome Type III: Experimental and Long-Term Clinical Data [J].

Chorin, Ehud ;

Hu, Dan ;

Antzelevitch, Charles ;

Hochstadt, Aviram ;

Belardinelli, Luiz ;

Zeltser, David ;

Barajas-Martinez, Hector ;

Rozovski, Uri ;

Rosso, Raphael ;

Adler, Arnon ;

Benhorin, Jesaia ;

Viskin, Sami .

CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 2016, 9 (10)

[36] Novel therapeutics for treatment of long-QT syndrome and torsade de pointes [J].

Khan, IA ;

Gowda, RM .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2004, 95 (01) :1-6

[37] QTc Behavior During Exercise and Genetic Testing for the Long-QT Syndrome [J].

Schwartz, Peter J. ;

Crotti, Lia .

CIRCULATION, 2011, 124 (20) :2181-2184

[38] NOS1AP Is a Genetic Modifier of the Long-QT Syndrome [J].

Crotti, Lia ;

Monti, Maria Cristina ;

Insolia, Roberto ;

Peljto, Anna ;

Goosen, Althea ;

Brink, Paul A. ;

Greenberg, David A. ;

Schwartz, Peter J. ;

George, Alfred L., Jr. .

CIRCULATION, 2009, 120 (17) :1657-1663

[39] Calcium Revisited New Insights Into the Molecular Basis of Long-QT Syndrome [J].

Giudicessi, John R. ;

Ackerman, Michael J. .

CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 2016, 9 (07)

[40] Utility of Treadmill Testing in Identification and Genotype Prediction in Long-QT Syndrome [J].

Wong, Jorge A. ;

Gula, Lorne J. ;

Klein, George J. ;

Yee, Raymond ;

Skanes, Allan C. ;

Krahn, Andrew D. .

CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 2010, 3 (02) :120-125

← 1 2 3 4 5 →