Long-QT Syndrome

被引：36
作者：
Kramer, Daniel B. [1 ]
Zimetbaum, Peter J. [1 ]
机构：
[1] Harvard Univ, Beth Israel Deaconess Med Ctr, Div Cardiovasc, Sch Med,Dept Med, Boston, MA 02215 USA
来源：
CARDIOLOGY IN REVIEW | 2011年 / 19卷 / 05期
关键词：
long QT syndrome; sudden cardiac death; GENOTYPE-PHENOTYPE CORRELATION; TORSADE-DE-POINTES; CARDIAC-ARRHYTHMIAS; MENSTRUAL-CYCLE; MOLECULAR-BASIS; LQT2; FORMS; HEART-RATE; EXERCISE; INTERVAL; RISK;
D O I：
10.1097/CRD.0b013e3182203504
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Acquired and hereditary long-QT syndromes are important causes of sudden cardiac death. Both categories are characterized by abnormally prolonged cardiac repolarization arising from a complex interaction between genetic and environmental factors. This produces a potentially dangerous substrate for polymorphic ventricular tachycardia and sudden cardiac death. In this review, the pathophysiologic, diagnostic, and prognostic features of long-QT syndromes, as well as recommendations regarding therapy, are reviewed.
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收藏
页码：217 / 225
页数：9
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