Dihydroxynortropane alkaloids from calystegine-producing plants

被引:37
作者
Asano, N
Yokoyama, K
Sakurai, M
Ikeda, K
Kizu, H
Kato, A
Arisawa, M
Höke, D
Dräger, B
Watson, AA
Nash, RJ
机构
[1] Hokuriku Univ, Fac Pharmaceut Sci, Kanazawa, Ishikawa 9201181, Japan
[2] Toyama Med & Pharmaceut Univ, Dept Hosp Pharm, Toyama 9300194, Japan
[3] Toyama Med & Pharmaceut Univ, Fac Pharmaceut Sci, Toyama 9300194, Japan
[4] Univ Halle Wittenberg, Inst Pharmazeut Biol, D-06120 Halle, Germany
[5] Inst Grassland & Environm Res, Aberystwyth SY23 3EB, Cardigan, Wales
关键词
Convolvulaceae; Solanaceae; dihydroxynortropane; calystegine; swainsonine;
D O I
10.1016/S0031-9422(01)00131-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Three dihydroxynortropanes, 2 alpha ,7 beta -dihydroxynortropane, 2 alpha ,3 beta -dihydroxynortropane, and 3 alpha ,7 beta -dihydroxynortropane, were isolated from calystegine-producing plants in the families Convolvulaceae and Solanaceae. 2 alpha ,7 beta -Dihydroxynortropane was isolated from six species in the Convolvulaceae whereas only Calystegia soldanella contained it and 2 alpha ,3 beta -dihydroxynortropane. Although neither of these were detectable in three species tested in the Solanaceae, 3 alpha ,7 beta -dihydroxynortropane was, however, isolated from Duboisia leichhardtii. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:721 / 726
页数:6
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