In recent years, the construction of a CFST arch bridge has developed rapidly; however, as a kind of structural system dominated by compression, with the increase of material strength and span, the stability of the main arch of the CFST arch bridge has become more and more important. In this paper, the finite element method is used to analyze the hanger force and the main arch stability of the long-span CFST arch bridge. Combined with the Shenzhen Rainbow Bridge project, the axial force of the hanger, the internal force, and stability of the main arch of the arch bridge are studied. In the establishment of the finite element model, considering the actual operation of the arch bridge, the model simulates the interaction between steel pipe and concrete, it studies the large deformation of CFST arch bridges, and the stress distribution and overall stability of the arch bridge are analyzed. The results show that the main deformation of the CFST arch bridge is the vertical displacement of the deck, and the axial force of most members of the upper arch ribs is greater than that of the lower arch ribs. The axial force and bending moment of the lower arch rib near the arch foot are larger, and the compressive stress of the arch foot is greater than that of other positions. The axial force of the suspender of the arch bridge is the largest at both ends of the hanger and the middle hanger, and the axial force of the other hanger is close to each other, and the axial force changes little under the same case. The buckling modes of the arch are mainly the lateral buckling or flexural buckling of the arch rib outside the plane, which indicates that the vertical stiffness of the arch bridge structure is larger than that of the transverse stiffness. The research results make the load-bearing mechanism of the CFST arch bridge more clear and also provide a certain reference for the design and construction of the CFST arch bridge.
