Stratus OCT Quality Control in Two Multi-Centre Multiple Sclerosis Clinical Trials

被引：9
作者：
Keltner, John L. [1 ,2 ]
Cello, Kimberly E. [1 ]
Balcer, Laura J. [3 ,4 ,5 ]
Calabresi, Peter A. [6 ]
Markowitz, Clyde E. [3 ]
Werner, John S. [1 ]
机构：
[1] Univ Calif Davis, Dept Ophthalmol & Vis Sci, Sacramento, CA 95817 USA
[2] Univ Calif Davis, Dept Neurol & Neurol Surg, Sacramento, CA 95817 USA
[3] Univ Penn, Sch Med, Dept Neurol, Philadelphia, PA 19104 USA
[4] Univ Penn, Sch Med, Dept Ophthalmol, Philadelphia, PA 19104 USA
[5] Univ Penn, Sch Med, Dept Epidemiol, Philadelphia, PA 19104 USA
[6] Johns Hopkins Univ Hosp, Dept Neurol, Baltimore, MD 21287 USA
来源：
NEURO-OPHTHALMOLOGY | 2011年 / 35卷 / 02期
关键词：
multiple sclerosis; neuro-ophthalmology; OCT; quality control; reading centre; OPTICAL COHERENCE TOMOGRAPHY; FIBER LAYER THICKNESS; OCULAR HYPERTENSION TREATMENT; AXONAL LOSS; NERVE; NEURITIS; ABNORMALITIES; SYSTEM; MS;
D O I：
10.3109/01658107.2011.557760
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The University of California (UC) Davis Reading Center evaluated 19,961 scans from 981 subjects in two multiple sclerosis therapeutic trials with the aim of determining the influence of optical coherence tomography quality control procedures on error rates. There was no optical coherence tomography technician certification in Trial 1, and technicians had very limited monitoring and feedback during the trial in view of the fact that data were received retrospectively. However, technicians were certified in Trial 2 and submitted data in accordance with the protocol. Trial 2 scans had higher signal strengths, fewer errors, and more useable data than the scans in Trial 1. Thus, certified technicians and prompt transmission of data for ongoing quality control monitoring provided higher quality data in multiple sclerosis trials.
引用
收藏
页码：57 / 64
页数：8
相关论文
共 31 条
  • [1] *C ZEISS MED INC, 2003, 2660021130591 CARL Z
  • [2] Reproducibility of optical coherence tomography in multiple sclerosis
    Cettomai, Deanna
    Pulicken, Mathew
    Gordon-Lipkin, Eliza
    Salter, Amber
    Frohman, Teresa C.
    Conger, Amy
    Zhang, Xiao
    Cutter, Gary
    Balcer, Laura J.
    Frohman, Elliot M.
    Calabresi, Peter A.
    [J]. ARCHIVES OF NEUROLOGY, 2008, 65 (09) : 1218 - 1222
  • [3] Relationship between retinal nerve fiber layer measurement and signal strength in optical coherence tomography
    Cheung, Carol Yim Lui
    Leung, Christopher Kai Shun
    Lin, Dusheung
    Pang, Chi-Pui
    Lam, Dennis Shun Chiu
    [J]. OPHTHALMOLOGY, 2008, 115 (08) : 1347 - 1351
  • [4] Optical coherence tomography 3: Delineation of the outer neural retinal boundary and its influence on retinal thickness measurements
    Costa, RA
    Calucci, D
    Skaf, M
    Cardillo, JA
    Castro, JC
    Melo, LA
    Martins, MC
    Kaiser, PK
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2004, 45 (07) : 2399 - 2406
  • [5] Quantifying tonal loss after optic neuritis with optical coherence tomography
    Costello, F
    Coupland, S
    Hodge, W
    Lorello, GR
    Koroluk, J
    Pan, YI
    Freedman, MS
    Zackon, DH
    Kardon, RH
    [J]. ANNALS OF NEUROLOGY, 2006, 59 (06) : 963 - 969
  • [6] The Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) Study System for Evaluation of Optical Coherence Tomograms SCORE Study Report 4
    Domalpally, Amitha
    Blodi, Barbara A.
    Scott, Ingrid U.
    Ip, Michael S.
    Oden, Neal L.
    Lauer, Andreas K.
    VanVeldhuisen, Paul C.
    [J]. ARCHIVES OF OPHTHALMOLOGY, 2009, 127 (11) : 1461 - 1467
  • [7] QUALITY ISSUES IN INTERPRETATION OF OPTICAL COHERENCE TOMOGRAMS IN MACULAR DISEASES
    Domalpally, Amitha
    Danis, Ronald P.
    Zhang, Baoyan
    Myers, Dawn
    Kruse, Christina N.
    [J]. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2009, 29 (06): : 775 - 781
  • [8] Relation of visual function to retinal nerve fiber layer thickness in multiple sclerosis
    Fisher, JB
    Jacobs, DA
    Markowitz, CE
    Galetta, SL
    Volpe, NJ
    Nano-Schiavi, ML
    Baier, ML
    Frohman, EM
    Winslow, H
    Frohman, TC
    Calabresi, PA
    Maguire, MG
    Cutter, GR
    Balcer, LJ
    [J]. OPHTHALMOLOGY, 2006, 113 (02) : 324 - 332
  • [9] Relationship of optic nerve and brain conventional and non-conventional MRI measures and retinal nerve fiber layer thickness, as assessed by OCT and GDx: A pilot study
    Frohman, Elliot M.
    Dwyer, Michael G.
    Frohman, Teresa
    Cox, Jennifer L.
    Salter, Amber
    Greenberg, Benjamin M.
    Hussein, Sara
    Conger, Amy
    Calabresi, Peter
    Balcer, Laura J.
    Zivadinov, Robert
    [J]. JOURNAL OF THE NEUROLOGICAL SCIENCES, 2009, 282 (1-2) : 96 - 105
  • [10] Optical coherence tomography: a window into the mechanisms of multiple sclerosis
    Frohman, Elliot M.
    Fujimoto, James G.
    Frohman, Teresa C.
    Calabresi, Peter A.
    Cutter, Gary
    Balcer, Laura J.
    [J]. NATURE CLINICAL PRACTICE NEUROLOGY, 2008, 4 (12): : 664 - 675
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