Neutralising antibody responses in cattle and sheep following booster vaccination with two commercial inactivated bluetongue virus serotype 8 vaccines

被引:9
|
作者
Bartram, David J. [1 ]
Heasman, Lindsay [2 ]
Batten, Carrie A. [3 ]
Oura, Christopher A. L. [3 ]
Plana-Duran, Joan [4 ]
Yuen, Ho Ming [5 ]
Wylie, Andrew D. M. [1 ]
机构
[1] Ft Dodge Anim Hlth, Southampton SO30 4QH, Hants, England
[2] Dawes Farm, Westpoint Vet Grp, Warnham RH12 3SH, W Sussex, England
[3] Inst Anim Hlth, Dept Arbovirol, Surrey GU24 ONF, England
[4] Ft Dodge Vet SA, Vall De Bianya Gerona 17813, Spain
[5] Univ Southampton, Southampton Gen Hosp, Sch Med, Southampton SO16 6YD, Hants, England
关键词
Bluetongue; Inactivated vaccine; Booster; Neutralising antibodies; EUROPE;
D O I
10.1016/j.tvjl.2010.04.001
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Cattle and sheep that had received a primary course of vaccination with an inactivated bluetongue virus serotype 8 (BTV-8) vaccine were booster vaccinated 6 or 12 months later with the homologous vaccine or an alternative inactivated BTV-8 vaccine and neutralising antibody responses were determined. Antibody titres to the alternative vaccine were significantly higher than to the homologous vaccine (P = 0.013) in cattle. There was no significant difference between the antibody responses to alternative and homologous vaccines in sheep. These data indicate that cattle and sheep primed with one inactivated BTV-8 vaccine may be effectively boosted with an alternative commercial inactivated BTV-8 vaccine. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:193 / 196
页数:4
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