GENOMIC MEDICINE Genomics and the Continuum of Cancer Care

被引:220
作者
McDermott, Ultan [1 ,2 ]
Downing, James R. [3 ]
Stratton, Michael R. [1 ,2 ]
机构
[1] Wellcome Trust Sanger Inst, Cambridge, England
[2] Inst Canc Res, Surrey, England
[3] St Jude Childrens Res Hosp, Memphis, TN 38105 USA
关键词
CELL LUNG-CANCER; GENE-EXPRESSION; ACQUIRED-RESISTANCE; POLY(ADP-RIBOSE) POLYMERASE; IMATINIB MESYLATE; MUTATIONS; BREAST; RECURRENCE; GEFITINIB; PREDICT;
D O I
10.1056/NEJMra0907178
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:340 / 350
页数:11
相关论文
共 55 条
[31]   Use of Cancer-Specific Genomic Rearrangements to Quantify Disease Burden in Plasma from Patients with Solid Tumors [J].
McBride, David J. ;
Orpana, Arto K. ;
Sotiriou, Christos ;
Joensuu, Heikki ;
Stephens, Philip J. ;
Mudie, Laura J. ;
Hamalainen, Eija ;
Stebbings, Lucy A. ;
Andersson, Leif C. ;
Flanagan, Adrienne M. ;
Durbecq, Virginie ;
Ignatiadis, Michail ;
Kallioniemi, Olli ;
Heckman, Caroline A. ;
Alitalo, Kari ;
Edgren, Henrik ;
Futreal, P. Andrew ;
Stratton, Michael R. ;
Campbell, Peter J. .
GENES CHROMOSOMES & CANCER, 2010, 49 (11) :1062-1069
[32]   Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition [J].
McCabe, Nuala ;
Turner, Nicholas C. ;
Lord, Christopher J. ;
Kluzek, Katarzyna ;
Bialkowska, Aneta ;
Swift, Sally ;
Giavara, Sabrina ;
O'Connor, Mark J. ;
Tutt, Andrew N. ;
Zdzienicka, Malgorzata Z. ;
Smith, Graeme C. M. ;
Ashworth, Alan .
CANCER RESEARCH, 2006, 66 (16) :8109-8115
[33]   Gefitinib or Carboplatin-Paclitaxel in Pulmonary Adenocarcinoma. [J].
Mok, Tony S. ;
Wu, Yi-Long ;
Thongprasert, Sumitra ;
Yang, Chih-Hsin ;
Chu, Da-Tong ;
Saijo, Nagahiro ;
Sunpaweravong, Patrapim ;
Han, Baohui ;
Margono, Benjamin ;
Ichinose, Yukito ;
Nishiwaki, Yutaka ;
Ohe, Yuichiro ;
Yang, Jin-Ji ;
Chewaskulyong, Busyamas ;
Jiang, Haiyi ;
Duffield, Emma L. ;
Watkins, Claire L. ;
Armour, Alison A. ;
Fukuoka, Masahiro .
NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (10) :947-957
[34]  
NOWELL PC, 1960, SCIENCE, V132, P1497
[35]   Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia [J].
O'Brien, SG ;
Guilhot, F ;
Larson, RA ;
Gathmann, I ;
Baccarani, M ;
Cervantes, F ;
Cornelissen, JJ ;
Fischer, T ;
Hochhaus, A ;
Hughes, T ;
Lechner, K ;
Nielsen, JL ;
Rousselot, P ;
Reiffers, J ;
Saglio, G ;
Shepherd, J ;
Simonsson, B ;
Gratwohl, A ;
Goldman, JM ;
Kantarjian, H ;
Taylor, K ;
Verhoef, G ;
Bolton, AE ;
Capdeville, R ;
Druker, BJ ;
Durrant, S ;
Schwarer, A ;
Joske, D ;
Seymour, J ;
Grigg, A ;
Ma, D ;
Arthur, C ;
Bradstock, K ;
Joshua, D ;
Louwagie, A ;
Martiat, P ;
Straetmans, N ;
Bosly, A ;
Shustik, C ;
Lipton, J ;
Forrest, D ;
Walker, I ;
Roy, DC ;
Rubinger, M ;
Bence-Bruckler, I ;
Kovacs, M ;
Turner, AR ;
Birgens, H ;
Bjerrum, O ;
Facon, T .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (11) :994-1004
[36]   Relationship Between Tumor Gene Expression and Recurrence in Four Independent Studies of Patients With Stage II/III Colon Cancer Treated With Surgery Alone or Surgery Plus Adjuvant Fluorouracil Plus Leucovorin [J].
O'Connell, Michael J. ;
Lavery, Ian ;
Yothers, Greg ;
Paik, Soonmyung ;
Clark-Langone, Kim M. ;
Lopatin, Margarita ;
Watson, Drew ;
Baehner, Frederick L. ;
Shak, Steven ;
Baker, Joffre ;
Cowens, J. Wayne ;
Wolmark, Norman .
JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (25) :3937-3944
[37]   Bcr-Abl kinase domain mutations, drug resistance, and the road to a cure for chronic myeloid leukemia [J].
O'Hare, Thomas ;
Eide, Christopher A. ;
Deininger, Michael W. N. .
BLOOD, 2007, 110 (07) :2242-2249
[38]   EGFR mutations in lung cancer:: Correlation with clinical response to gefitinib therapy [J].
Paez, JG ;
Jänne, PA ;
Lee, JC ;
Tracy, S ;
Greulich, H ;
Gabriel, S ;
Herman, P ;
Kaye, FJ ;
Lindeman, N ;
Boggon, TJ ;
Naoki, K ;
Sasaki, H ;
Fujii, Y ;
Eck, MJ ;
Sellers, WR ;
Johnson, BE ;
Meyerson, M .
SCIENCE, 2004, 304 (5676) :1497-1500
[39]   A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer [J].
Paik, S ;
Shak, S ;
Tang, G ;
Kim, C ;
Baker, J ;
Cronin, M ;
Baehner, FL ;
Walker, MG ;
Watson, D ;
Park, T ;
Hiller, W ;
Fisher, ER ;
Wickerham, DL ;
Bryant, J ;
Wolmark, N .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (27) :2817-2826
[40]   Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain [J].
Pao, W ;
Miller, VA ;
Politi, KA ;
Riely, GJ ;
Somwar, R ;
Zakowski, MF ;
Kris, MG ;
Varmus, H .
PLOS MEDICINE, 2005, 2 (03) :225-235