Supramolecular Systems of BATPPH2 and Its Zn Complex with Cyclodextrins

A new porphyrin 5-(4-Benzamido Phenyl)- 10, 15, 20-triphenylporphyrin (BATPPH(2)) and its Zn complex (BATPPZn) were synthesized and characterized by elemental analyses, IR, UV-Vis spectra and H-1 NMR respectively. In neutral phosphate buffer solution, the inclusive complexation behavior of BATPPH(2) and BATPPZn with alpha-cyclodextrin(alpha-CD), beta-cyclodextrin (beta-CD), and gamma-cyclodextrin (gamma-CD) have been examined by means of Ultraviolet-visible spectrometry and fluorescence spectroscopy. The formation constants (K) of BATPPH(2) and BATPPZn for the inclusion complexes have been estimated from the absorbance and fluorescence intensity changes. The K gamma-CD value (7.20 x 10(5)) of BATPPH(2)-gamma-CD is bigger than that of the other two CDs, that indicates gamma-CD have the strongest inclusion ability, zinc ion, coordination destabilizes the inclusion complex of porphyrin and cyclodextrin. In addition H-1 NMR data and 2D-NOESY spectra support the inclusion conformation of the supramolecular system(BATPPH(2)-gamma-CD and BATPPZn-gamma-CD).