Non-invasive blood glucose measurement using quantum cascade laser

被引：3
|
作者：
Matsuura, Y. [1 ]
Koyama, T. [1 ]
机构：
[1] Tohoku Univ, Grad Sch Biomed Engn, Sendai, Miyagi 9808579, Japan
来源：
QUANTUM SENSING AND NANO ELECTRONICS AND PHOTONICS XVI | 2019年 / 10926卷
关键词：
Blood glucose; ATR spectroscopy; Quantum cascade laser; Hollow optical fiber;
D O I：
10.1117/12.2506845
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
A non-invasive blood glucose measurement method using quantum cascade lasers (QCLs) oscillated in mid-infrared region is introduced. A mid-infrared spectroscopy system equipped with a combination of QCLs as light sources and hollow-optical fibers as beam delivery media is developed. As a wavelength of QCL, the wavenumber of 1152 cm(-1) that exhibited strong correlation with blood glucose in the optical absorption of human lips is firstly chosen. Then 1186 cm(-1) where glucose shows no absorption is also chosen as a reference to remove effects of the baseline variation. By using the QCL-based system, it is shown that the differential absorption between these wavelengths exhibits high correlation with blood glucose level.
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页数：7
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