HLA analysis of Sri Lankan Sinhalese predicts North Indian origin

被引：15
作者：
Malavige, G. N.
Rostron, T.
Seneviratne, S. L.
Fernando, S.
Sivayogan, S.
Wijewickrama, A.
Ogg, G. S. [1 ]
机构：
[1] Univ Oxford, Weatherall Inst Mol Med, Cutaneous Immunol Grp, Oxford OX3 9DS, England
[2] Univ Oxford, Weatherall Inst Mol Med, Cutaneous Immunol Grp, MRC Human Immunol Unit, Oxford OX3 9DS, England
[3] Manchester Royal Infirm, Dept Clin Immunol, Manchester M13 9WL, Lancs, England
[4] Univ Sri Jayewardenepura, Dept Microbiol, Nugegoda, Sri Lanka
[5] Univ Sri Jayewardenepura, Dept Community Med, Nugegoda, Sri Lanka
[6] Infect Dis Hosp, Colombo, Sri Lanka
[7] Churchill Hosp, Dept Dermatol, Oxford OX3 7LJ, England
来源：
INTERNATIONAL JOURNAL OF IMMUNOGENETICS | 2007年 / 34卷 / 05期
基金：
英国医学研究理事会;
关键词：
D O I：
10.1111/j.1744-313X.2007.00698.x
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The origin of the Sinhalese population of Sri Lanka is debated. We subtyped HLA-A*02 in 101 Sinhalese and observed a preponderance of the rare allele HLA-A*0211 which was similar to reported frequencies in northern India. Taken with low-resolution typing for the remaining A, B, C, DR and DQ alleles, these data suggest a North Indian origin for the Sri Lankan Sinhalese.
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收藏
页码：313 / 315
页数：3
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