Biocompatible, polyampholyte microgel particles

被引：14

作者：

Bradley, Melanie

Vincent, Brian

Burnett, Gary

机构：

[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England

[2] GSK, New Prod Res, Oral Hlth Care, Weybridge KT13 0DE, Surrey, England

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 2007年 / 60卷 / 09期

关键词：

D O I：

10.1071/CH07098

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Biocompatible, polyampholyte microgel particles have been prepared by the acid hydrolysis of t-butyl groups within (2-diethylamino) ethyl methacrylate-co-t-butyl methacrylate microgel particles to give (2-diethylamino) ethyl methacrylate-co-methacrylic acid microgel particles. The hydrodynamic diameter and electrophoretic mobility of both the pre-hydrolyzed and post-hydrolyzed microgel particles have been investigated as a function of pH for three microgel dispersions differing in their monomer compositions. The swelling properties and isoelectric point pH are shown to depend on the monomer composition.

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页码：646 / 650

页数：5

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