Biocompatible, polyampholyte microgel particles

被引：14
|
作者：
Bradley, Melanie
Vincent, Brian
Burnett, Gary
机构：
[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England
[2] GSK, New Prod Res, Oral Hlth Care, Weybridge KT13 0DE, Surrey, England
来源：
AUSTRALIAN JOURNAL OF CHEMISTRY | 2007年 / 60卷 / 09期
关键词：
D O I：
10.1071/CH07098
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Biocompatible, polyampholyte microgel particles have been prepared by the acid hydrolysis of t-butyl groups within (2-diethylamino) ethyl methacrylate-co-t-butyl methacrylate microgel particles to give (2-diethylamino) ethyl methacrylate-co-methacrylic acid microgel particles. The hydrodynamic diameter and electrophoretic mobility of both the pre-hydrolyzed and post-hydrolyzed microgel particles have been investigated as a function of pH for three microgel dispersions differing in their monomer compositions. The swelling properties and isoelectric point pH are shown to depend on the monomer composition.
引用
收藏
页码：646 / 650
页数：5
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