Enhancement of C2C12 differentiation by perfluorocarbon-mediated oxygen delivery

被引：9

作者：

Fujita, Hideaki ^{[1
]}

Shimizu, Kazunori ^{[1
]}

Morioka, Yuki ^{[1
]}

Nagamori, Eiji ^{[1
]}

机构：

[1] Toyota Cent Res & Dev Labs Inc, Aichi 4801192, Japan

来源：

JOURNAL OF BIOSCIENCE AND BIOENGINEERING | 2010年 / 110卷 / 03期

关键词：

Muscle; PFC; Perfusion; Active tension; Collagen; SKELETAL-MUSCLE; CELL-LINE; DEGRADATION; CONTRACTILE; FABRICATION; MYOBLASTS; MYOTUBES;

D O I：

10.1016/j.jbiosc.2010.02.012

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

We have studied the effect of enhanced oxygen delivery by perfluorocarbons on the differentiation of C2C12 cells. The extent of differentiation was assessed by means of phase contrast/fluorescence microscopy, active tension measurement and the glucose consumption/lactate production rates. We found that enhanced oxygen delivery is suitable for full differentiation of C2C12 cells. (C) 2010, The Society for Biotechnology, Japan. All rights reserved.

引用

页码：359 / 362

页数：4

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