Collagen-apatite nanocomposite membranes for guided bone regeneration

被引：81
作者：
Song, Ju-Ha
Kim, Hyoun-Ee [1 ]
Kim, Hae-Won
机构：
[1] Dankook Univ, Sch Dent, Dept Dent Biomat, Cheonan 330714, South Korea
[2] Seoul Natl Univ, Sch Mat Sci & Engn, Seoul 151744, South Korea
来源：
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS | 2007年 / 83B卷 / 01期
关键词：
collagen; nanomaterials/nanophase; membrane; hydroxy(1)lapatite;
D O I：
10.1002/jbm.b.30790
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Collagen-apatite nanocomposite is regarded as a potential biomaterial because of its composition and structure, which are similar to those of human hard tissues. However, there have been few investigations of its mechanical and biological benefits in direct comparison with a collagen equivalent. Herein, we successfully produced a biomedical membrane made of a nanocomposite, and systemically evaluated the mechanical, chemical, and biological properties of the nanocomposite in comparison with those of pure collagen. The results showed that significant improvements were achieved by the nanocomposite approach, particularly in terms of the mechanical strength and chemical stability. The present findings point to the potential usefulness of the collagen-apatite nanocomposite membrane in the field of guided bone regeneration (GBR). (c) 2007 Wiley Periodicals, Inc.
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收藏
页码：248 / 257
页数：10
相关论文
共 28 条
[1]   Evaluation of a poly-l-lactic acid membrane and membrane fixing pin for guided tissue regeneration on bone defects in dogs [J].
Amano, Y ;
Ota, M ;
Sekiguchi, K ;
Shibukawa, Y ;
Yamada, S .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 2004, 97 (02) :155-163
[2]   Influence of different collagen species on physico-chemical properties of crosslinked collagen matrices [J].
Angele, P ;
Abke, J ;
Kujat, R ;
Faltermeier, H ;
Schumann, D ;
Nerlich, M ;
Kinner, B ;
Englert, C ;
Ruszczak, Z ;
Mehrl, R ;
Mueller, R .
BIOMATERIALS, 2004, 25 (14) :2831-2841
[3]  
ASBOE M, 1995, BR J ORAL MAXILLOFAC, V33, P312
[4]   FT-IR study for hydroxyapatite/collagen nanocomposite cross-linked by glutaraldehyde [J].
Chang, MC ;
Tanaka, J .
BIOMATERIALS, 2002, 23 (24) :4811-4818
[5]   Chemical synthesis of hydroxyapatite/poly(ε-caprolactone) composites [J].
Choi, DW ;
Marra, KG ;
Kumta, PN .
MATERIALS RESEARCH BULLETIN, 2004, 39 (03) :417-432
[6]  
COAST WD, 1996, J MOL CELL CARDIOL, V28, P441
[7]   Cross-linking of dermal sheep collagen using a water-soluble carbodiimide [J].
Damink, LHHO ;
Dijkstra, PJ ;
vanLuyn, MJA ;
vanWachem, PB ;
Nieuwenhuis, P ;
Feijen, J .
BIOMATERIALS, 1996, 17 (08) :765-773
[8]  
Du C, 2000, J BIOMED MATER RES, V50, P518, DOI 10.1002/(SICI)1097-4636(20000615)50:4<518::AID-JBM7>3.0.CO
[9]  
2-W
[10]   Comparative study of three different membranes for guided bone regeneration of rat cranial defects [J].
Dupoirieux, L ;
Pourquier, D ;
Picot, MC ;
Neves, M .
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2001, 30 (01) :58-62
123