Synthesis of N-(2-Hydroxyaryl)benzotriazoles via Metal-Free O-Arylation and N-O Bond Cleavage

被引：25

作者：

Wang, Zhi-Xin ^{[1
]}

Shi, Wei -Min ^{[1
]}

Bi, Hong-Yan ^{[1
]}

Li, Xiao-Hua ^{[1
]}

Su, Gui-Fa ^{[1
]}

Mo, Dong-Liang ^{[1
]}

机构：

[1] Guangxi Normal Univ, Sch Chem & Pharmaceut Sci, Minist Sci & Technol China, State Key Lab Chem & Mol Engn Med Resources, 15 Yu Cai Rd, Guilin 541004, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2016年 / 81卷 / 17期

基金：

中国国家自然科学基金;

关键词：

DIARYLIODONIUM SALTS SYNTHESIS; BENZYNE CLICK CHEMISTRY; ALKENYL BORONIC ACIDS; CHANNEL ACTIVATORS; ARYL; DERIVATIVES; BENZOTRIAZOLES; IMIDAZOLES; LIGAND; AZIDES;

D O I：

10.1021/acs.joc.6b01390

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A metal-free method for synthesis of N-(2-hydroxyaryl)benzotriazoles via O-arylation of N-hydroxybenzotriazoles with readily available diaryliodonium salts and sequential N-O bond cleavage under mild conditions has been developed. The [3,3]-rearrangement of N-O bond cleavage could take place on the N instead of C atom. The reaction was compatible with diverse functional groups and a new type of P,N-ligand was synthesized in three steps.

引用

页码：8014 / 8021

页数：8

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