Survey of Antimicrobial Resistance in Clinical Burkholderia pseudomallei Isolates over Two Decades in Northeast Thailand

被引：71

作者：

Wuthiekanun, Vanaporn ^{[1
]}

Amornchai, Premjit ^{[1
]}

Saiprom, Natnaree ^{[2
]}

Chantratita, Narisara ^{[1
,2
]}

Chierakul, Wirongrong ^{[1
,3
]}

Koh, Gavin C. K. W. ^{[1
,7
]}

Chaowagul, Wipada ^{[5
]}

Day, Nicholas P. J. ^{[1
,6
]}

Limmathurotsakul, Direk ^{[1
,4
]}

Peacock, Sharon J. ^{[1
,2
,7
]}

机构：

[1] Mahidol Univ, Fac Trop Med, Mahidol Oxford Trop Med Res Unit, Bangkok 10400, Thailand

[2] Mahidol Univ, Fac Trop Med, Dept Microbiol & Immunol, Bangkok 10400, Thailand

[3] Mahidol Univ, Fac Trop Med, Dept Clin Trop Med, Bangkok 10400, Thailand

[4] Mahidol Univ, Fac Trop Med, Dept Trop Hyg, Bangkok 10400, Thailand

[5] Sappasithiprasong Hosp, Dept Med, Ubon Ratchathani, Thailand

[6] Univ Oxford, Nuffield Dept Clin Med, Churchill Hosp, Ctr Clin Vaccinol & Trop Med, Oxford, England

[7] Univ Cambridge, Addenbrookes Hosp, Dept Med, Cambridge CB2 2QQ, England

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2011年 / 55卷 / 11期

基金：

英国惠康基金;

关键词：

SEVERE MELIOIDOSIS; PSEUDOMONAS-PSEUDOMALLEI; CEFTAZIDIME; SUSCEPTIBILITIES; INFECTION; THERAPY;

D O I：

10.1128/AAC.05517-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A 21-year survey conducted in northeast Thailand of antimicrobial resistance to parenteral antimicrobial drugs used to treat melioidosis identified 24/4,021 (0.6%) patients with one or more isolates resistant to ceftazidime (n = 8), amoxicillin-clavulanic acid (n = 4), or both drugs (n = 12). Two cases were identified at admission, and the remainder were detected a median of 15 days after starting antimicrobial therapy. Resistance to carbapenem drugs was not detected. These findings support the current prescribing recommendations for melioidosis.

引用

页码：5388 / 5391

页数：4

共 23 条

[1] Oral fluoroquinolones for maintenance treatment of melioidosis [J].

Chaowagul, W ;

Suputtamongkul, Y ;

Smith, MD ;

White, NJ .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1997, 91 (05) :599-601

[2] Randomized controlled trial of granulocyte colony-stimulating factor for the treatment of severe sepsis due to melioidosis in Thailand [J].

Cheng, Allen C. ;

Limmathurotsakul, Direk ;

Chierakul, Wirongrong ;

Getchalarat, Nongluk ;

Wuthiekanun, Vanaporn ;

Stephens, Dianne P. ;

Day, Nicholas P. J. ;

White, Nicholas J. ;

Chaowagul, Wipada ;

Currie, Bart J. ;

Peacock, Sharon J. .

CLINICAL INFECTIOUS DISEASES, 2007, 45 (03) :308-314

[3]

Chetchotisakd Ploenchan, 2001, American Journal of Tropical Medicine and Hygiene, V64, P24

[4] Two randomized controlled trials of ceftazidime alone versus ceftazidime in combination with trimethoprim-sulfamethoxazole for the treatment of severe melioidosis [J].

Chierakul, W ;

Anunnatsiri, S ;

Short, JM ;

Maharjan, B ;

Mootsikapun, P ;

Simpson, AJH ;

Limmathurotsakul, D ;

Cheng, AC ;

Stepniewska, K ;

Newton, PN ;

Chaowagul, W ;

White, NJ ;

Peacock, SJ ;

Day, NP ;

Chetchotisakd, P .

CLINICAL INFECTIOUS DISEASES, 2005, 41 (08) :1105-1113

[5]

Clinical and Laboratory Standards Institute, 2010, M100S20 CLIN LAB STA, V30, P40

[6] The Epidemiology and Clinical Spectrum of Melioidosis: 540 Cases from the 20 Year Darwin Prospective Study [J].

Currie, Bart J. ;

Ward, Linda ;

Cheng, Allen C. .

PLOS NEGLECTED TROPICAL DISEASES, 2010, 4 (11)

[7] THE ANTIMICROBIAL SUSCEPTIBILITY OF PSEUDOMONAS-PSEUDOMALLEI - EMERGENCE OF RESISTANCE INVITRO AND DURING TREATMENT [J].

DANCE, DAB ;

WUTHIEKANUN, V ;

CHAOWAGUL, W ;

WHITE, NJ .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1989, 24 (03) :295-309

[8] Multilocus sequence typing and evolutionary relationships among the causative agents of melioidosis and glanders, Burkholderia pseudomallei and Burkholderia mallei [J].

Godoy, D ;

Randle, G ;

Simpson, AJ ;

Aanensen, DM ;

Pitt, TL ;

Kinoshita, R ;

Spratt, BG .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (05) :2068-2079

[9] Comparison of the susceptibilities of Burkholderia pseudomallei to meropenem and ceftazidime by conventional and intracellular methods [J].

Inglis, TJJ ;

Rodrigues, F ;

Rigby, P ;

Norton, R ;

Currie, BJ .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (08) :2999-3005

[10] Antibiotic susceptibility of Burkholderia pseudomallei from tropical northern Australia and implications for therapy of melioidosis [J].

Jenney, AWJ ;

Lum, G ;

Fisher, DA ;

Currie, BJ .

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2001, 17 (02) :109-113

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