Ionic liquids-based monolithic columns: Recent advancements and their applications for high-efficiency separation and enrichment

被引:16
作者
Chen, Rui [1 ]
Zhou, Hongwei [2 ]
Liu, Mingchen [1 ]
Yan, Hongyuan [3 ]
Qiao, Xiaoqiang [1 ]
机构
[1] Hebei Univ, Coll Pharmaceut Sci, Key Lab Analyt Sci & Technol Hebei Prov, Key Lab Med Chem & Mol Diag,Minist Educ, Baoding 071002, Peoples R China
[2] China Acad Chinese Med Sci, Inst Basic Res Clin Evaluat, Beijing 100700, Peoples R China
[3] Hebei Univ, Coll Publ Hlth, Key Lab Med Chem & Mol Diag, Minist Educ, Baoding 071002, Peoples R China
基金
中国国家自然科学基金; 中国博士后科学基金;
关键词
Ionic liquids; Monolithic column; Fabrication method; High efficiency separation; Enrichment; SOLID-PHASE MICROEXTRACTION; POROUS POLYMER MONOLITHS; STATIONARY PHASES; IMPRINTED MONOLITH; SMALL MOLECULES; MACROPOROUS POLYMER; PROTEIN SEPARATION; CHROMATOGRAPHY; FABRICATION; SOLVENTS;
D O I
10.1016/j.trac.2018.11.026
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Because of their excellent physicochemical characteristics, ionic liquids (ILs) have been widely reported as new monomers to fabricate versatile monolithic columns with improved separation efficiency and excellent selectivity. In this study, a systematic summary of the recently reported ILs-based monolithic columns was performed. We paid much attention to the characteristics of the introduced ILs as well as the fabrication methods for the monolithic columns. Furthermore, the ILs-based monolithic columns were respectively discussed based on their applications in high performance liquid chromatography, capillary electrochromatography and solid phase extraction. Moreover, ILs as the porogenic solution for fabrication of monolithic columns were also included. (C) 2018 Elsevier B.V. All rights reserved.
引用
收藏
页码:1 / 12
页数:12
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