Travoprost/timolol fixed combination

被引:6
作者
Herceg, Michael [1 ]
Noecker, Robert [1 ]
机构
[1] Univ Pittsburgh, Sch Med, UPMC Eye Ctr, Pittsburgh, PA 15213 USA
关键词
DuoTrav; eye drop; fixed combination; glaucoma; ocular hypertension; timolol; travatan; travoprost;
D O I
10.1517/14656566.9.6.1059
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Background: Travoprost and timolol are topical ocular hypotensive medications that have been used in the treatment of glaucoma. The fixed combination eye drop, Duotrav (travoprost 0.004% and timolol maleate 0.5%), has recently been introduced into the market. Objective: In this paper, the results of clinical trials and existing data on the performance of travoprost/timolol are discussed and analyzed. Methods: Appopriate studies for review were identified using PubMed. Studies selected for review compared efficacy and side-effect profile of fixed combination travoprost/timolol with travoprost and timolol used concomitantly, latanoprost and timolol used concomitantly, fixed combination latanoprost/timolol, travoprost alone and timolol alone. Results/conclusion: Fixed combination eye drops such as travoprost/timolol offer the potential benefits of increased patient adherence, reduced exposure to preservatives, and reduced cost.
引用
收藏
页码:1059 / 1065
页数:7
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