The Osteosarcoradionecrosis as an Unfavorable Result Following Head and Neck Tumor Ablation and Microsurgical Reconstruction

被引:7
作者
Deek, Nidal Farhan A. L. [1 ]
Wei, Fu-Chan [1 ]
机构
[1] Chang Gung Univ, Coll Med, Chang Gung Mem Hosp, Dept Plast & Reconstruct Surg, 199 Tun Hwa North Rd, Taipei 10591, Taiwan
关键词
Osteoradionecrosis; Osteosarcoradionecrosis; Radiotherapy; RADIATION-THERAPY; OSTEORADIONECROSIS; TISSUE; FLAP; JAWS; CLASSIFICATION; RADIOTHERAPY; EXPERIENCE; MANAGEMENT; PROPOSAL;
D O I
10.1016/j.cps.2016.05.009
中图分类号
R61 [外科手术学];
学科分类号
摘要
Osteoradionecrosis is preferably called osteosarcoradionecrosis to adequately cover the scope of the problem: multitissue necrosis. The changes following radiotherapy and leading to necrosis are further classified into 2 phases based on improved understanding of the underlying mechanisms. The reversible-damage phase could respond to the medical treatment, while the irreversible damage phase or osteosarcoradionecrosis may benefit from complete resection and free flap reconstruction. The role of ablation and reconstruction in paving the road for the development of osteosarcoradionecrosis is discussed, a case study provided, and a refined reconstructive approach proposed.
引用
收藏
页码:753 / +
页数:8
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  • [1] REDUCING THE RISK OF XEROSTOMIA AND MANDIBULAR OSTEORADIONECROSIS: THE POTENTIAL BENEFITS OF INTENSITY MODULATED RADIOTHERAPY IN ADVANCED ORAL CAVITY CARCINOMA
    Ahmed, Merina
    Hansen, Vibeke N.
    Harrington, Kevin J.
    Nutting, Christopher M.
    [J]. MEDICAL DOSIMETRY, 2009, 34 (03) : 217 - 224
  • [2] Early cellular alterations in bone after radiation therapy and its relation to osteoradionecrosis
    Al-Nawas, B
    Duschner, H
    Grötz, KA
    [J]. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2004, 62 (08) : 1045 - 1045
  • [3] New foundations in understanding osteonecrosis of the jaws
    Assael, LA
    [J]. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2004, 62 (02) : 125 - 126
  • [4] Osteoradionecrosis of the mandible after oromandibular cancer surgery
    Celik, N
    Wei, FC
    Chen, HC
    Cheng, MH
    Huang, WC
    Tsai, FC
    Chen, YC
    [J]. PLASTIC AND RECONSTRUCTIVE SURGERY, 2002, 109 (06) : 1875 - 1881
  • [5] Osteoradionecrosis of the jaws-a current overview-part 1
    Chrcanovic B.R.
    Reher P.
    Sousa A.A.
    Harris M.
    [J]. Oral and Maxillofacial Surgery, 2010, 14 (1) : 3 - 16
  • [6] Microvascular free tissue transfer for treatment of osteoradionecrosis of the maxilla
    Coskunfirat, OK
    Wei, FC
    Huang, WC
    Cheng, MH
    Yang, WG
    Chang, YM
    [J]. PLASTIC AND RECONSTRUCTIVE SURGERY, 2005, 115 (01) : 54 - 60
  • [7] Changing trends and the role of medical management on the outcome of patients treated for osteoradionecrosis of the mandible: experience from a regional head and neck unit
    D'Souza, J.
    Lowe, D.
    Rogers, S. N.
    [J]. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 2014, 52 (04) : 356 - 362
  • [8] Major healing of refractory mandible osteoradionecrosis after treatment combining pentoxifylline and tocopherol: A phase II trial
    Delanian, S
    Depondt, J
    Lefaix, JL
    [J]. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2005, 27 (02): : 114 - 123
  • [9] The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway
    Delanian, S
    Lefaix, JL
    [J]. RADIOTHERAPY AND ONCOLOGY, 2004, 73 (02) : 119 - 131
  • [10] OSTEORADIONECROSIS - CLINICAL-EXPERIENCE AND A PROPOSAL FOR CLASSIFICATION
    EPSTEIN, JB
    WONG, FLW
    STEVENSONMOORE, P
    [J]. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 1987, 45 (02) : 104 - 110