Out on the farm with DNA vaccines

被引：34

作者：

Beard, CW ^{[1
]}

Mason, PW ^{[1
]}

机构：

[1] USDA ARS, Plum Isl Anim Dis Ctr, Greenport, NY 11944 USA

来源：

NATURE BIOTECHNOLOGY | 1998年 / 16卷 / 13期

关键词：

agricultural biotechnology; vaccine development; livestock/poultry;

D O I：

10.1038/4298

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

DNA vaccination is a rapidly developing technology that offers new approaches for the prevention of disease. This technology may permit the production of new vaccines against diseases that have no current vaccine, as well as allowing the development of improved vaccines to replace existing products. We describe how DNA vaccination is being developed for use in commercial animal production, with an emphasis on viral diseases, and discuss the existing hurdles to its development and use.

引用

页码：1325 / 1328

页数：4

共 36 条

[1]

Babiuk LA, 1998, CURR TOP MICROBIOL, V226, P90

[2]

BRAUN R, 1997, VACCINE RES, V6, P151

[3] Antibody response in mice inoculated with DNA expressing foot-and-mouth disease virus capsid proteins [J].

Chinsangaram, J ;

Beard, C ;

Mason, PW ;

Zellner, MK ;

Ward, G ;

Grubman, MJ .

JOURNAL OF VIROLOGY, 1998, 72 (05) :4454-4457

[4] BOVINE HERPESVIRUS-1 - IMMUNE-RESPONSES IN MICE AND CATTLE INJECTED WITH PLASMID DNA [J].

COX, GJM ;

ZAMB, TJ ;

BABIUK, LA .

JOURNAL OF VIROLOGY, 1993, 67 (09) :5664-5667

[5]

Davis HL, 1998, CURR TOP MICROBIOL, V226, P57

[6] Induction of protective immunity to Theileria annulata using two major merozite surface antigens presented by different delivery systems [J].

dOliveira, C ;

Feenstra, A ;

Vos, H ;

Osterhaus, ADME ;

Shiels, BR ;

Cornelissen, AWCA ;

Jongejan, F .

VACCINE, 1997, 15 (16) :1796-1804

[7] ''Naked'' DNA transfer technology for genetic vaccination against infectious disease [J].

Fazio, VM .

RESEARCH IN VIROLOGY, 1997, 148 (02) :101-108

[8] Protection of pigs against Aujeszky's disease by DNA vaccination [J].

Gerdts, V ;

Jons, A ;

Makoschey, B ;

Visser, N ;

Mettenleiter, TC .

JOURNAL OF GENERAL VIROLOGY, 1997, 78 :2139-2146

[9] Serum and colostrum antibody responses induced by jet-injection of sheep with DNA encoding a Cryptosporidium parvum antigen [J].

Jenkins, M ;

Kerr, D ;

Fayer, R ;

Wall, R .

VACCINE, 1995, 13 (17) :1658-1664

[10] Cross-protection among lethal H5N2 Influenza viruses induced by DNA vaccine to the hemagglutinin [J].

Kodihalli, S ;

Haynes, JR ;

Robinson, HL ;

Webster, RG .

JOURNAL OF VIROLOGY, 1997, 71 (05) :3391-3396

← 1 2 3 4 →