[68 Ga]Ga-PSMA-11 Small Bowel Uptake in Crohn's Disease: Revisiting the "Non-specificity" of PSMA Ligands

被引：6
作者：
Chandekar, Kunal Ramesh [1 ]
Tanigassalam, Sindhu [1 ]
Kavanal, Anwin Joseph [1 ]
Singh, Harmandeep [1 ]
Bhattacharya, Anish [1 ]
Mavuduru, Ravimohan Suryanarayan [2 ]
机构：
[1] Postgrad Inst Med Educ & Res, Dept Nucl Med, Chandigarh 160012, India
[2] Postgrad Inst Med Educ & Res, Dept Urol, Chandigarh, India
来源：
NUCLEAR MEDICINE AND MOLECULAR IMAGING | 2022年 / 56卷 / 02期
关键词：
Prostate-specific membrane antigen (PSMA); Prostate cancer; PET; CT; Inflammatory bowel disease (IBD); Crohn's disease; MEMBRANE ANTIGEN; EXPRESSION; PET;
D O I：
10.1007/s13139-021-00732-4
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
The rapidly evolving clinical utility of prostate-specific membrane antigen (PSMA) PET/CT as an imaging modality for prostate cancer (PCa) has brought to the forefront a multitude of non-prostatic diseases also exhibiting PSMA radioligand uptake. We report a case of a 71-year-old male with PCa who underwent PSMA PET/CT for recurrence evaluation. The scan demonstrated [68 Ga]Ga-PSMA-11 uptake in the distal ileum. Retrospective enquiry revealed that the patient was a known case of Crohn's disease. This case highlights an uncommon finding of PSMA radioligand uptake in the distal small bowel (non-prostatic benign pathological uptake) in a patient with known Crohn's disease, which may be misinterpreted in the evaluation of PCa.
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收藏
页码：102 / 104
页数：3
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