Regenerative medicine improve neurodegenerative diseases

被引：10

作者：

Ashraf, Seyedeh Sara ^{[1
,2
,3
]}

Sarmadi, Vahid Hosseinpour ^{[2
,3
,4
]}

Larijani, Ghazaleh ^{[1
,2
]}

Garahgheshlagh, Soheila Naderi ^{[5
,6
]}

Ramezani, Sara ^{[7
,8
]}

Moghadamifar, Soraya ^{[9
]}

Mohebi, Seyedeh Lena ^{[2
,3
]}

Milan, Peiman Brouki ^{[3
,4
]}

Haramshahi, Seyed Mohammad Amin ^{[4
,6
]}

Ahmadirad, Nooshin ^{[2
]}

Amini, Naser ^{[2
,3
]}

机构：

[1] Islamic Azad Univ, Dept Biol, Sci & Res Branch, Tehran, Iran

[2] Iran Univ Med Sci, Cellular & Mol Res Ctr, Tehran, Iran

[3] Iran Univ Med Sci, Inst Regenerat Med, Tehran, Iran

[4] Iran Univ Med Sci, Fac Adv Technol Med, Dept Tissue Engn & Regenerat Med, Tehran, Iran

[5] Iran Univ Med Sci, Burn Res Ctr, Tehran, Iran

[6] Iran Univ Med Sci, Hazrat Fatemeh Hosp, Sch Med, Dept Plast & Reconstruct Surg, Tehran, Iran

[7] Guilan Univ Med Sci, Neurosci Res Ctr, Guilan Rd Trauma Res Ctr, Rasht, Guilan, Iran

[8] Guilan Univ Med Sci, Guilan Rd Trauma Res Ctr, Rasht, Iran

[9] Amirkabir Univ Technol, Dept Text Engn, Tehran, Iran

来源：

CELL AND TISSUE BANKING | 2022年 / 24卷 / 3期

关键词：

Regenerative medicine; Neurodegenerative disorders; Cell therapy; Gene therapy; Engineered nanoparticles; MESENCHYMAL STEM-CELLS; CENTRAL-NERVOUS-SYSTEM; HUMAN ADIPOSE-TISSUE; GENE-THERAPY; BEHAVIORAL IMPROVEMENT; PARKINSONS-DISEASE; ALZHEIMERS-DISEASE; PROLONGS SURVIVAL; IN-VITRO; DELIVERY;

D O I：

10.1007/s10561-022-10062-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Regenerative medicine is a subdivision of medicine that improves methods to regrow, repair or replace unhealthy cells and tissues to return to normal function. Cell therapy, gene therapy, nanomedicine as choices used to cure neurodegenerative disease. Recently, studies related to the treatment of neurodegenerative disorders have been focused on stem cell therapy and Nano-drugs beyond other than regenerative medicine. Hence, by data from experimental models and clinical trials, we review the impact of stem cell therapy, gene therapy, and nanomedicine on the treatment of Alzheimer's disease (AD), Parkinson's disease (PD), and Amyotrophic lateral sclerosis (ALS). Indeed, improved knowledge and continued research on gene therapy and nanomedicine in treating Alzheimer's disease, Parkinson's disease, and Amyotrophic lateral sclerosis lead to advancements in effective and practical treatments for neurodegenerative diseases.

引用

页码：639 / 650

页数：12

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