DIAGNOSIS AND MANAGEMENT OF PAGET'S DISEASE OF BONE - SERIES OF 8 CASES

被引：0
作者：
Kazan de Oliveira, Felipe Augusto [1 ]
Eloi Pinto, Fabio Fernando [1 ]
Sardenberg, Trajano [1 ]
Cacao Pereira, Gilberto Jose [1 ]
Curcelli, Emilio Carlos [1 ]
Penna, Valter [1 ]
机构：
[1] Univ Estadual Sao Paulo Julio de Mesquita Filho U, Fac Med Botucatu, Botucatu, SP, Brazil
来源：
ACTA ORTOPEDICA BRASILEIRA | 2019年 / 27卷 / 01期
关键词：
Paget's Disease; Osteitis Deformans; Neoplasm Metastasis;
D O I：
10.1590/1413-785220192701161107
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Paget's disease of bone is a chronic condition characterized by focal abnormalities of absorption and formation of bone, and it may lead to anatomical deformities, pain, fractures, and malignant transformation. It is common in the UK, Australia, New Zealand, and North America and has a strong hereditary component, affecting first- to third-degree relatives. The etiology remains unclear and treatment is based on control of the disease with bisphosphonates, with the aim of relieving symptoms and correcting laboratory abnormalities. Surgical treatment may also be necessary to correct deformities or treat pathological fractures. This study evaluated the management and course of 8 patients with Paget's disease of bone, followed in the Orthopedic Clinic of this hospital. Among these patients, 1 had concomitant advanced prostate carcinoma, highlighting the association between Paget's disease and secondary bone diseases that can affect the differential diagnosis.
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收藏
页码：31 / 32
页数：2
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