Preparation of Graphene/Chitosan Nanocomposite Scaffold and Its Application in Fracture Treatment

被引:2
作者
Cao, Le [1 ,2 ,3 ]
Lian, Ruiming [4 ]
Wu, Yongping [1 ,2 ,3 ]
Xiao, Shining [1 ,2 ,3 ]
Miao, Xudong [1 ,2 ,3 ]
机构
[1] Zhejiang Univ, Affiliated Hosp 2, Sch Med, Dept Orthoped Surg, Hangzhou 310000, Zhejiang, Peoples R China
[2] Zhejiang Univ, Orthoped Res Inst, Dept Orthoped Surg, Hangzhou 310000, Zhejiang, Peoples R China
[3] Key Lab Motor Syst Dis Res & Precis Therapy Zhejia, Hangzhou 310000, Zhejiang, Peoples R China
[4] Second Peoples Hosp Yueqing, Dept Orthoped Surg, Wenzhou 325000, Zhejiang, Peoples R China
关键词
Graphene; Chitosan; Stent Equipment; Fracture Treatment; Medical Application; COMPOSITE; MICROSPHERES;
D O I
10.1166/jbn.2022.3362
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
In the early stages, patients with fractures often have massive bleeding, wasting coagulopathy, and injuries to other parts, but in the later stages, they are prone to various complications, leading to high mortality and disability. This study focuses on the preparation of nanomaterial graphene/chitosan scaffolds and their application in fracture treatment. This article first summarizes the current state of nanomaterial scaffolds, then describes their preparation methods, and finally describes their application in fracture treatment. In patients with fractures, the nanomaterial graphene/chitosan scaffold can provide a favorable rehabilitation environment at the fracture site. When combined with the auto repair ability of human tissues, it has the potential to accelerate patient recovery. The graphene/chitosan scaffold has a molecular structure similar to natural bone, making it more suitable for human bone rehabilitation than ordinary fixed scaffolds. The best time between IP: 846247 10 O M n, 31 Oct 2022 08:0627 stent implantation and surgery is half a month, which can significantly reduce the risk of postoperative complications. Reoperation for more than 18 days is an independent risk factor for local cancer recurrence. Therefore, using nanomaterial De ivered by Ingenta graphene/chitosan scaffolds in fracture treatment is safe, effective, and feasible. Further future research in this direction is warranted.
引用
收藏
页码:1659 / 1667
页数:9
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