Mixed cortical adenoma and composite pheochromocytoma-ganglioneuroma: an unusual corticomedullary tumor of the adrenal gland

被引：30

作者：

Lau, Sean K. ^{[1
]}

Chu, Peiguo G. ^{[1
]}

Weiss, Lawrence M. ^{[1
]}

机构：

[1] City Hope Natl Med Ctr, Div Pathol, Duarte, CA 91010 USA

来源：

ANNALS OF DIAGNOSTIC PATHOLOGY | 2011年 / 15卷 / 03期

关键词：

Adrenal gland; Corticomedullary tumor; Composite pheochromocytoma; CUSHINGS-SYNDROME; PATIENT; ASSOCIATION; FEATURES; BENIGN; ENTITY;

D O I：

10.1016/j.anndiagpath.2010.02.005

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Adrenal neoplasms composed of more than one cell type and demonstrating a mixed histologic appearance are exceedingly rare. We report the clinical and pathologic features of a morphologically distinctive tumor of the adrenal gland composed of cortical, chromaffin, and neural cells. Histologically, the tumor consisted of intermixed areas of proliferating cortical cells resembling adrenal cortical adenoma, neoplastic chromaffin cells consistent with pheochromocytoma, and a ganglioneuromatous stroma. The presence of the cortical, medullary, and neural components within the tumor was confirmed by immunohistochemical studies. The present case serves to broaden the morphologic spectrum of mixed tumors that may be encountered in the adrenal gland. (C) 2011 Elsevier Inc. All rights reserved.

引用

页码：185 / 189

页数：5

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