Synthesis of 1,1A′-[methylenebis(oxy)]bis[3-alkyl-3-(2-haloethyl)triaz-1-ene 2-oxides]

被引：9

作者：

Pokhvisneva, G. V. ^{[1
]}

Ternikova, T. V. ^{[1
]}

Smirnov, G. A. ^{[1
]}

Gordeev, P. B. ^{[1
]}

Nikitin, S. V. ^{[1
]}

Luk 'yanov, O. A. ^{[1
]}

机构：

[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2017年 / 66卷 / 07期

基金：

俄罗斯科学基金会;

关键词：

1,1 '-[methylenebis(oxy)]bis[3-alkyl-3-(2-haloethyl)triaz-1-ene 2-oxides; 1,1 '-[methylenebis(oxy)]bis[3-alkyl-3-(2-hydroxyethyl)triaz-1-ene 2-oxides; alkylation; chlorination; bromination; iodination; METHYLENE-BIS(1-OXY-3,3-DIALKYL-1-TRIAZENE 2-OXIDES); DERIVATIVES; SYSTEMS;

D O I：

10.1007/s11172-017-1878-5

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A method for the synthesis of promising nitric oxide donors in living organisms, 1,1A '-[methylenebis(oxy)]bis[3-alkyl-3-(2-haloethyl)triaz-1-ene 2-oxides] was elaborated. The method involved replacement of hydroxy groups of the corresponding 1,1A '-[methylenebis(oxy)]bis[3-alkyl-3-(2-hydroxyethyl)triaz-1-ene 2-oxides] by halogen atoms and, in some cases, the exchange of one halogen atom for another.

引用

页码：1234 / 1239

页数：6

共 50 条

[41] Simple One-Pot Synthesis of Novel 5-(3,5-Dialkyl-1H-pyrazol-1-yl)-2-ethoxy-1,4,2λ5-diazaphosphole 2-Oxides [J].

Assiri, M. A. ;

Ali, T. E. ;

Alzahrani, A. Y. ;

Salem, M. A. .

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2023, 59 (02) :285-289

[42] Temperature-Dependent Product Selectivity in the VilsmeierHaack Reaction on Bis(phenylhydrazones) of Bis(aroylmethyl) Sulfides (=1,1′-[Thiobis(methylene)]bis[arylmethanone] Bis(2-phenylhydrazones)): Synthesis of 3-Aroylindoles (=Aryl(1H-indol-3-yl)methanones) [J].

Paul, Nidhin ;

Muthusubramanian, Shanmugam .

HELVETICA CHIMICA ACTA, 2013, 96 (03) :452-457

[43] Reaction of γ-sultines with electrophilic reagents. 1. Bromination of 3,5-diaryl-1,2-oxathiolane 2-oxides [J].

E. V. Grigor'ev ;

L. G. Saginova .

Chemistry of Heterocyclic Compounds, 2003, 39 (1) :113-118

[44] Consecutive alkylation-reduction reactions of 2H-1,2,3-benzothiadiazine 1,1-dioxide derivatives. Synthesis of 2-alkyl-, 3-alkyl-, and 2,3-dialkyl-3,4-dihydro-2H-1,2,3-benzothiadiazine 1,1-dioxides [J].

Porcs-Makkay, Marta ;

Pandur, Angela ;

Simig, Gyula ;

Volk, Balazs .

TETRAHEDRON, 2015, 71 (01) :44-50

[45] Synthesis, Characterization, and Antibacterial Activity of [Cu2(L1)3(NCS)]•CH3CN and [Cu2Br2(L2)2(μ1,1-N3)2] [J].

Li, Jian-Nan .

SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY, 2013, 43 (07) :832-837

[46] Synthesis of 1-Substituted 3-Alkyl-1,2,3-triazol-3-ium-5-olates [J].

Yu. I. Nein ;

A. Yu. Polyakova ;

Yu. Yu. Morzherin ;

E. A. Savel’eva ;

Yu. A. Rozin ;

V. A. Bakulev .

Russian Journal of Organic Chemistry, 2004, 40 :879-883

[47] Synthesis of 1-substituted 3-alkyl-1,2,3-triazol-3-ium-5-olates [J].

Nein, YI ;

Polyakova, AY ;

Morzherin, YY ;

Savel'eva, EA ;

Rozin, YA ;

Bakulev, VA .

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2004, 40 (06) :879-883

[48] Synthesis of 3,3′-methylenebis(4-hydroxyquinolin-2(1H)-ones) of prospective anti-COVID-19 drugs [J].

Aly, Ashraf A. ;

Hassan, Alaa A. ;

Mohamed, Asmaa H. ;

Osman, Esraa M. ;

Braese, Stefan ;

Nieger, Martin ;

Ibrahim, Mahmoud A. A. ;

Mostafa, Sara M. .

MOLECULAR DIVERSITY, 2021, 25 (01) :461-471

[49] Synthesis, Characterization and Biological Evaluation Against Influenza Virus Agonists of (N′E,N′"E)-2,2′-[[1,1′-Biphenyl]-4,4′-dihylbis(oxy)]bis (N′-arylmethyleneacetohydrazides) [J].

El Ashry, El Sayed H. ;

Din, Zia Ud ;

Soomro, Zahid H. ;

Rehman, Wajid ;

Shah, Muhammad Raza ;

El Kilany, Yeldez ;

Naesens, Lieve ;

Boraei, Ahmed T. A. .

LETTERS IN ORGANIC CHEMISTRY, 2014, 11 (03) :168-173

[50] Synthesis of Functionalized Acetophenones by Formal [3+3] Cyclocondensations of 1,3-Bis(silyloxy)-1,3-butadienes with 3-Alkoxy- and 3-Silyloxy-2-acetyl-2-en-1-ones [J].

Dede, Ruediger ;

Riahi, Abdolmajid ;

Shkoor, Mohanad ;

Yawer, Mirza A. ;

Hussain, Ibrar ;

Kelzhanova, Nazken ;

Abilov, Zharylkasyn A. ;

Falodun, Abiodun ;

Goerls, Helmar ;

Langer, Peter .

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2013, 68 (09) :1021-1030

← 1 2 3 4 5 →