Synthesis of 1,1A′-[methylenebis(oxy)]bis[3-alkyl-3-(2-haloethyl)triaz-1-ene 2-oxides]

被引：9

作者：

Pokhvisneva, G. V. ^{[1
]}

Ternikova, T. V. ^{[1
]}

Smirnov, G. A. ^{[1
]}

Gordeev, P. B. ^{[1
]}

Nikitin, S. V. ^{[1
]}

Luk 'yanov, O. A. ^{[1
]}

机构：

[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2017年 / 66卷 / 07期

基金：

俄罗斯科学基金会;

关键词：

1,1 '-[methylenebis(oxy)]bis[3-alkyl-3-(2-haloethyl)triaz-1-ene 2-oxides; 1,1 '-[methylenebis(oxy)]bis[3-alkyl-3-(2-hydroxyethyl)triaz-1-ene 2-oxides; alkylation; chlorination; bromination; iodination; METHYLENE-BIS(1-OXY-3,3-DIALKYL-1-TRIAZENE 2-OXIDES); DERIVATIVES; SYSTEMS;

D O I：

10.1007/s11172-017-1878-5

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A method for the synthesis of promising nitric oxide donors in living organisms, 1,1A '-[methylenebis(oxy)]bis[3-alkyl-3-(2-haloethyl)triaz-1-ene 2-oxides] was elaborated. The method involved replacement of hydroxy groups of the corresponding 1,1A '-[methylenebis(oxy)]bis[3-alkyl-3-(2-hydroxyethyl)triaz-1-ene 2-oxides] by halogen atoms and, in some cases, the exchange of one halogen atom for another.

引用

页码：1234 / 1239

页数：6

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