Inhibitors of DNA polymerase β from Schoepfia californica

被引:42
作者
Chen, J
Zhang, YH
Wang, LK
Sucheck, SJ
Snow, AM
Hecht, SM
机构
[1] Univ Virginia, Dept Chem, Charlottesville, VA 22901 USA
[2] Univ Virginia, Dept Biol, Charlottesville, VA 22901 USA
关键词
D O I
10.1039/a807053i
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Fractionation of a hexane extract prepared from the plant Schoepfia californica was carried out by bioassay guided fractionation, affording five inhibitors of DNA polymerase beta; four of these were shown to be anacardic acid and structurally related derivatives, while the fifth was oleic acid.
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页码:2769 / 2770
页数:2
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