Postmortem biochemical examination of synovial fluid - a preliminary study

被引:55
作者
Madea, B [1 ]
Kreuser, C [1 ]
Banaschak, S [1 ]
机构
[1] Univ Bonn, Inst Med Legale, D-53111 Bonn, Germany
关键词
postmortem examination; synovial fluid; metabolic status;
D O I
10.1016/S0379-0738(00)00372-8
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Vitreous humor chemistry is used for postmortem analysis since serum values of many components are thought to be reflected in vitreous humor and to be stable for a prolonged postmortem interval (pmi). A similar isolated compartment to vitreous humor is synovial fluid which up to now was hardly used for postmortem chemistry. The aim of the present examination was to compare the values of various analytes in both fluid compartments to get first hints for the reliability of the examination of synovial fluid. Therefore, in 74 cases of sudden death both fluids were taken and analysed for natrium, potassium, calcium, chloride, urea, creatinine, and glucose. The results show that the examination of synovial fluid as compared to vitreous humor is a reliable method to get hints on the premortal metabolic status since most analytes are stable postmortem. The range of all values is comparable in both fluids. The time course of glucose concentrations and, much more important, potassium concentrations is nearly similar If no vitreous humor is available synovial fluid may be used with all precautions in diagnosis known from vitreous humor. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:29 / 35
页数:7
相关论文
共 15 条
[1]  
ALYBAEVA K N, 1987, Sudebno-Meditsinskaya Ekspertiza, V30, P18
[2]  
ARTHUR RE, 1983, ARTHRITIS RHEUM, V26, P1499
[3]  
AUDRILICKY I, 1965, BLUTALKOHOL, V3, P503
[5]   POSTMORTEM CHEMISTRY UPDATE - EMPHASIS ON FORENSIC APPLICATION [J].
COE, JI .
AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY, 1993, 14 (02) :91-117
[6]  
GASTMEIER G, 1982, KRIMINALISTIK FORENS, V47, P41
[7]  
GATTER RA, 1984, PRACTICAL HDB JOINT
[8]   PERMEABILITY OF HUMAN SYNOVIAL MEMBRANE TO PLASMA PROTEINS - RELATIONSHIP TO MOLECULAR SIZE AND INFLAMMATION [J].
KUSHNER, I ;
SOMERVILLE, JA .
ARTHRITIS AND RHEUMATISM, 1971, 14 (05) :560-+
[9]   REFERENCES FOR DETERMINING THE TIME OF DEATH BY POTASSIUM IN VITREOUS-HUMOR [J].
MADEA, B ;
HENSSGE, C ;
HONIG, W ;
GERBRACHT, A .
FORENSIC SCIENCE INTERNATIONAL, 1989, 40 (03) :231-243
[10]  
Madea B, 1996, RECHTSMEDIZIN, V6, P141