Oscillations, resonances and noise: basis of flexible neuronal pattern generation

被引：34
作者：
Braun, HA
Voigt, K
Huber, MT
机构：
[1] Univ Marburg, Inst Physiol, Lab Neurodynam, D-35037 Marburg, Germany
[2] Univ Marburg, Dept Psychiat, D-35037 Marburg, Germany
来源：
BIOSYSTEMS | 2003年 / 71卷 / 1-2期
关键词：
neuronal impulse pattern; subthreshold oscillations; noise effects; computer model; cold receptors;
D O I：
10.1016/S0303-2647(03)00108-4
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Modulation of neuronal impulse pattern is examined by means of a simplified Hodgkin-Huxley type computer model which refers to experimental recordings of cold receptor discharges. This model essentially consists of two potentially oscillating subsystems: a spike generator and a subthreshold oscillator. With addition of noise the model successfully mimics the major types of experimentally recorded impulse patterns and thereby elucidate different resonance behaviors. (1) There is a range of rhythmic spiking or bursting where the spike generator is strongly coupled to the subthreshold oscillator. (2) There is a pacemaker activity of more complex interactions where the spike generator has overtaken part of the control. (3) There is a situation where the two subsystems are decoupled and only resonate with the help of noise. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：39 / 50
页数：12
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