Albumin nanoparticles as nanocarriers for drug delivery: Focusing on antibody and nanobody delivery and albumin-based drugs

被引：63

作者：

Karami, Elmira ^{[1
]}

Behdani, Mahdi ^{[1
]}

Kazemi-Lomedasht, Fatemeh ^{[1
]}

机构：

[1] Pasteur Inst Iran, Biotechnol Res Ctr, Venom & Biotherapeut Mol Lab, Tehran, Iran

来源：

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY | 2020年 / 55卷

关键词：

Serum albumin; Nanoparticle; Nanocarrier; Nanobody; HUMAN SERUM-ALBUMIN; GROWTH-FACTOR RECEPTOR; PROTEIN NANOPARTICLES; THERAPEUTIC AGENTS; CONTROLLED-RELEASE; DOMAIN ANTIBODIES; CANCER-THERAPY; HALF-LIFE; PACLITAXEL; SYSTEM;

D O I：

10.1016/j.jddst.2019.101471

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Given that albumin has important roles in human body, it can be used in the field of medicine and disease treatment. In recent years, albumin is used as a carries in disease diagnosis and treatment. Therapeutic drugs have some disadvantages such as low solubility, shallow absorption and many side effects all of which can be overcome using nanocarriers like albumin. In this article, we reviewed different types of albumin (human, bovine, and egg) and various methods in producing and transporting albumin. We also discussed the ability of albumin as nanoparticle in reducing drug side effects and increasing their stability.

引用

页数：8

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