Iodocyclization of 1,4-dihydropyridines

被引：17
|
作者：
Lavilla, R [1 ]
Coll, O [1 ]
Nicolàs, M [1 ]
Bosch, J [1 ]
机构：
[1] Univ Barcelona, Fac Pharm, Organ Chem Lab, E-08028 Barcelona, Spain
来源：
TETRAHEDRON LETTERS | 1998年 / 39卷 / 28期
关键词：
cyclization; halogenation; pyridines; oxazolidines;
D O I：
10.1016/S0040-4039(98)00912-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Iodine (or related species) addition to 1,4-dihydropyridinls, with properly attached substituents at the nitrogen atom, leads to the corresponding 3-iodotetrahydlopyridinium ions, which undergo an internal nucleophilic attack to furnish regio- and stereoselectively iodobi(poly)heterocyclic ring systems in good yields. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：5089 / 5092
页数：4
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