Sugar-sweetened carbonated beverage consumption and coronary artery calcification in asymptomatic men and women

被引：26

作者：

Chun, Sohyun ^{[1
,2
]}

Choi, Yuni ^{[1
]}

Chang, Yoosoo ^{[1
,3
,4
]}

Cho, Juhee ^{[1
,4
,5
,6
,7
]}

Zhang, Yiyi ^{[5
,6
,7
]}

Rampal, Sanjay ^{[5
,6
,7
,8
]}

Zhao, Di ^{[5
,6
,7
]}

Ahn, Jiin ^{[1
]}

Suh, Byung-Seong ^{[3
]}

Pastor-Barriuso, Roberto ^{[9
,10
]}

Lima, Joao A. C. ^{[11
]}

Chung, Eun Chul ^{[2
,12
]}

Shin, Hocheol ^{[1
,13
,14
]}

Guallar, Eliseo ^{[5
,6
,7
]}

Ryu, Seungho ^{[1
,3
,4
]}

机构：

[1] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Total Healthcare Ctr, Ctr Cohort Studies,Sch Med, Seoul, South Korea

[2] Sungkyunkwan Univ, Samsung Med Ctr, Int Hlth Serv, Sch Med, Seoul, South Korea

[3] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Occupat & Environm Med, Sch Med, Seoul, South Korea

[4] Sungkyunkwan Univ, Dept Clin Res Design & Evaluat, SAIHST, Seoul, South Korea

[5] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA

[6] Johns Hopkins Univ, Dept Med, Bloomberg Sch Publ Hlth, Baltimore, MD USA

[7] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Welch Ctr Prevent Epidemiol & Clin Res, Baltimore, MD USA

[8] Univ Malaya, Fac Med, Dept Social & Prevent Med, Julius Ctr, Kuala Lumpur, Malaysia

[9] Carlos III Inst Hlth, Natl Ctr Epidemiol, Madrid, Spain

[10] Consortium Biomed Res Epidemiol & Publ Hlth CIBER, Madrid, Spain

[11] Johns Hopkins Univ, Sch Med, Div Cardiol, Baltimore, MD USA

[12] Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Dept Radiol, Seoul, South Korea

[13] Kangbuk Samsung Hosp, Dept Family Med, Seoul 100742, South Korea

[14] Sungkyunkwan Univ, Sch Med, Seoul, South Korea

来源：

AMERICAN HEART JOURNAL | 2016年 / 177卷

关键词：

SOFT DRINK CONSUMPTION; MIDDLE-AGED WOMEN; HEART-DISEASE; WEIGHT-GAIN; METABOLIC SYNDROME; GLYCEMIC INDEX; RISK-FACTORS; OBESITY; FRUCTOSE; CALCIUM;

D O I：

10.1016/j.ahj.2016.03.018

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background Sugar-sweetened carbonated beverage consumption has been linked to obesity, metabolic syndrome, type 2 diabetes, and clinically manifest coronary heart disease, but its association with subclinical coronary heart disease remains unclear. We investigated the relationship between sugar-sweetened carbonated beverage consumption and coronary artery calcium (CAC) in a large study of asymptomatic men and women. Methods This was a cross-sectional study of 22,210 adult men and women who underwent a comprehensive health screening examination between 2011 and 2013 (median age 40 years). Sugar-sweetened carbonated beverage consumption was assessed using a validated food frequency questionnaire, and CAC was measured by cardiac computed tomography. Multivariable-adjusted CAC score ratios and 95% CIs were estimated from robust Tobit regression models for the natural logarithm (CAC score +1). Results The prevalence of detectable CAC (CAC score >0) was 11.7% (n = 2,604). After adjustment for age; sex; center; year of screening examination; education level; physical activity; smoking; alcohol intake; family history of cardiovascular disease; history of hypertension; history of hypercholesterolemia; and intake of total energy, fruits, vegetables, and red and processed meats, only the highest category of sugar-sweetened carbonated beverage consumption was associated with an increased CAC score compared with the lowest consumption category. The multivariable-adjusted CAC ratio comparing participants who consumed >= 5 sugar-sweetened carbonated beverages per week with nondrinkers was 1.70 (95% CI, 1.03-2.81). This association did not differ by clinical subgroup, including participants at low cardiovascular risk. Conclusion Our findings suggest that high levels of sugar-sweetened carbonated beverage consumption are associated with a higher prevalence and degree of CAC in asymptomatic adults without a history of cardiovascular disease, cancer, or diabetes.

引用

页码：17 / 24

页数：8

共 34 条

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