Cloning of genes differentially expressed in the cerebellum during postnatal rat development

被引:0
|
作者
Akopyan, AN [1 ]
Baka, ID [1 ]
Chestkov, AV [1 ]
Bukhman, VL [1 ]
Georgiev, GP [1 ]
机构
[1] RUSSIAN ACAD SCI,INST GENE BIOL,MOSCOW 117334,RUSSIA
来源
GENETIKA | 1996年 / 32卷 / 07期
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D O I
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中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
To identify genes differentially expressed in the developing rat cerebellum, a subtractive cDNA cloning procedure, followed by differential screening, was used. Four novel genes, MB, MF, 3E7, and 3C6, the transcriptional activity of which changed by a factor of five during cerebellar development, were isolated. The genes obtained were differentially expressed in different regions of the central nervous system. Variations in the levels of corresponding transcripts in the brain cortex and cerebellum were also recorded during postnatal rat development.
引用
收藏
页码:886 / 895
页数:10
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