Mechanisms of Zika Virus Infection and Neuropathogenesis

被引:41
作者
Olagnier, David [1 ]
Muscolini, Michela [2 ]
Coyne, Carolyn B. [3 ]
Diamond, Michael S. [4 ,5 ,6 ]
Hiscott, John [2 ]
机构
[1] McGill Univ, Jewish Gen Hosp, Lady Davis Inst, Montreal, PQ, Canada
[2] Fdn Cenci Bolognetti, Ist Pasteur, Viale Regina Elena 291, I-00161 Rome, Italy
[3] Univ Pittsburgh, Dept Microbiol & Mol Genet, Pittsburgh, PA USA
[4] Washington Univ, Sch Med, Dept Med, Ctr Human Immunol & Immunotherapy Programs, St Louis, MO 63110 USA
[5] Washington Univ, Sch Med, Dept Mol Microbiol, Ctr Human Immunol & Immunotherapy Programs, St Louis, MO 63110 USA
[6] Washington Univ, Sch Med, Dept Pathol & Immunol, Ctr Human Immunol & Immunotherapy Programs, St Louis, MO USA
基金
美国国家卫生研究院;
关键词
CAUSES BIRTH-DEFECTS; CELLS; TRANSMISSION; ORGANOIDS; MODELS; MICE;
D O I
10.1089/dna.2016.3404
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A spotlight has been focused on the mosquito-borne Zika virus (ZIKV) because of its epidemic outbreak in Brazil and Latin America, as well as the severe neurological manifestations of microcephaly and Guillain Barre syndrome associated with infection. In this review, we discuss the recent literature on ZIKV-host interactions, including new mechanistic insight concerning the basis of ZIKV-induced neuropathogenesis.
引用
收藏
页码:367 / 372
页数:6
相关论文
共 44 条
[1]  
Aliota MT, 2016, PLOS NEGLECT TROP D, V10, DOI [10.1371/journal.pntd.0004682, 10.1371/journal.pntd.0004750]
[2]   NS5 of Dengue Virus Mediates STAT2 Binding and Degradation [J].
Ashour, Joseph ;
Laurent-Rolle, Maudry ;
Shi, Pei-Yong ;
Garcia-Sastre, Adolfo .
JOURNAL OF VIROLOGY, 2009, 83 (11) :5408-5418
[3]   Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection [J].
Bayer, Avraham ;
Lennemann, Nicholas J. ;
Ouyang, Yingshi ;
Bramley, John C. ;
Morosky, Stefanie ;
De Azeved Marques, Ernesto Torres, Jr. ;
Cherry, Sara ;
Sadovsky, Yoel ;
Coyne, Carolyn B. .
CELL HOST & MICROBE, 2016, 19 (05) :705-712
[4]   Missing link: Animal models to investigate whether Zika causes birth defects [J].
Becker, Rachel .
NATURE MEDICINE, 2016, 22 (03) :225-227
[5]   Zika Virus Infection in Pregnant Women in Rio de Janeiro [J].
Brasil, P. ;
Pereira, J. P., Jr. ;
Moreira, M. E. ;
Ribeiro Nogueira, R. M. ;
Damasceno, L. ;
Wakimoto, M. ;
Rabello, R. S. ;
Valderramos, S. G. ;
Halai, U. -A. ;
Salles, T. S. ;
Zin, A. A. ;
Horovitz, D. ;
Daltro, P. ;
Boechat, M. ;
Gabaglia, C. Raja ;
Carvalho de Sequeira, P. ;
Pilotto, J. H. ;
Medialdea-Carrera, R. ;
Cotrim da Cunha, D. ;
Abreu de Carvalho, L. M. ;
Pone, M. ;
Machado Siqueira, A. ;
Calvet, G. A. ;
Rodrigues Baiao, A. E. ;
Neves, E. S. ;
Nassar de Carvalho, P. R. ;
Hasue, R. H. ;
Marschik, P. B. ;
Einspieler, C. ;
Janzen, C. ;
Cherry, J. D. ;
Bispo de Filippis, A. M. ;
Nielsen-Saines, K. .
NEW ENGLAND JOURNAL OF MEDICINE, 2016, 375 (24) :2321-2334
[6]   Guillain-Barre syndrome associated with Zika virus infection [J].
Brasil, Patricia ;
Sequeira, Patricia Carvalho ;
Freitas, Andrea D'Avila ;
Zogbi, Heruza Einsfeld ;
Calvet, Guilherme Amaral ;
de Souza, Rogerio Valls ;
Siqueira, Andre Machado ;
Lima de Mendonca, Marcos Cesar ;
Ribeiro Nogueira, Rita Maria ;
Bispo de Filippis, Ana Maria ;
Solomon, Tom .
LANCET, 2016, 387 (10026) :1482-1482
[7]   Zika Virus as a Cause of Neurologic Disorders [J].
Broutet, Nathalie ;
Krauer, Fabienne ;
Riesen, Maurane ;
Khalakdina, Asheena ;
Almiron, Maria ;
Aldighieri, Sylvain ;
Espinal, Marcos ;
Low, Nicola ;
Dye, Christopher .
NEW ENGLAND JOURNAL OF MEDICINE, 2016, 374 (16) :1506-1509
[8]   Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study [J].
Calvet, Guilherme ;
Aguiar, Renato S. ;
Melo, Adriana S. O. ;
Sampaio, Simone A. ;
de Filippis, Ivano ;
Fabri, Allison ;
Araujo, Eliane S. M. ;
de Sequeira, Patricia C. ;
de Mendonca, Marcos C. L. ;
de Oliveira, Louisi ;
Tschoeke, Diogo A. ;
Schrago, Carlos G. ;
Thompson, Fabiano L. ;
Brasil, Patricia ;
dos Santos, Flavia B. ;
Nogueira, Rita M. R. ;
Tanurit, Amilcar ;
de Filippis, Ana M. B. .
LANCET INFECTIOUS DISEASES, 2016, 16 (06) :653-660
[9]   Human cerebral organoids recapitulate gene expression programs of fetal neocortex development [J].
Camp, J. Gray ;
Badsha, Farhath ;
Florio, Marta ;
Kanton, Sabina ;
Gerber, Tobias ;
Wilsch-Braeuninger, Michaela ;
Lewitus, Eric ;
Sykes, Alex ;
Hevers, Wulf ;
Lancaster, Madeline ;
Knoblich, Juergen A. ;
Lachmann, Robert ;
Paeaebo, Svante ;
Huttner, Wieland B. ;
Treutlein, Barbara .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (51) :15672-15677
[10]   Guillain-Barre Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study [J].
Cao-Lormeau, Van-Mai ;
Blake, Alexandre ;
Mons, Sandrine ;
Lastere, Stephane ;
Roche, Claudine ;
Vanhomwegen, Jessica ;
Dub, Timothee ;
Baudouin, Laure ;
Teissier, Anita ;
Larre, Philippe ;
Vial, Anne-Laure ;
Decam, Christophe ;
Choumet, Valerie ;
Halstead, Susan K. ;
Willison, Hugh J. ;
Musset, Lucile ;
Manuguerra, Jean-Claude ;
Despres, Philippe ;
Fournier, Emmanuel ;
Mallet, Henri-Pierre ;
Musso, Didier ;
Fontanet, Arnaud ;
Neil, Jean ;
Ghawche, Frederic .
LANCET, 2016, 387 (10027) :1531-1539