2-α-hydroxybenzhydryl- and 2,7-di(α-hydroxybenzhydryl)-1,8-bis(dimethylamino)naphthalenes:: the first examples of stabilization of in/out proton sponge conformers by intramolecular hydrogen bonding.: The most flattened amino group ever participating in IHB

被引：19

作者：

Pozharskii, AF

Ryabtsova, OV

Ozeryanskii, VA

Degtyarev, AV

Starikova, ZA

Sobczyk, L

Filarowski, A

机构：

[1] Rostov State Univ, Dept Chem, Rostov Na Donu 344090, Russia

[2] Russian Acad Sci, AN Nesmeyanov Organomet Cpds Inst, Moscow 119991, Russia

[3] Univ Wroclaw, Fac Chem, PL-50383 Wroclaw, Poland

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 23期

基金：

俄罗斯基础研究基金会;

关键词：

D O I：

10.1016/j.tetlet.2005.04.045

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-(alpha-Hydroxybenzhydryl)-6 and 2,7-di(alpha-hydroxybenzhydryl)-1,8-bis(dimethylamino)naphthalenes 8 have been shown to exist in crystals as in/out conformers stabilized by O-H center dot center dot center dot N intramolecular hydrogen bonding. In agreement with X-ray studies, the NMR data are also consistent with 7 retaining its in/out form in solution, whilst for 8 superimposed equilibrating in/out out/in conformers are observed. (c) 2005 Elsevier Ltd. All rights reserved.

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页码：3973 / 3976

页数：4

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