Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications

被引：13

作者：

Martin, ME ^{[1
]}

Wabuyele, MB ^{[1
]}

Panjehpour, M ^{[1
]}

Phan, MN ^{[1
]}

Overholt, BF ^{[1
]}

DeNovo, RC ^{[1
]}

Moyers, T ^{[1
]}

Song, SG ^{[1
]}

Vo-Dinh, T ^{[1
]}

机构：

[1] Oak Ridge Natl Lab, Ctr Adv Biomed Photon, Oak Ridge, TN 37831 USA

来源：

Advanced Biomedical and Clinical Diagnostic Systems III | 2005年 / 5692卷

关键词：

hyperspectral fluorescence spectroscopy; acousto-optic tunable filters; medical imaging; biomedical optics; laser-induced fluorescence;

D O I：

10.1117/12.604445

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

We present the principles and applications of our dual-modality fluorescence and reflectance hyperspectral imaging (DMHSI) system. In this paper we report on background work done using laser induced fluorescence (LIF) by the group in the early detection of esophageal cancer. We then demonstrate the capabilities of our new DMHSI system. The system consists of a laser, endoscope, AOTF, and two cameras coupled with optics and electronics. Preliminary results, performed on mouse tissue, show that the system can delineate normal and malignant tissue regions in real-time.

引用

页码：133 / 139

页数：7

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