Microwave-Assisted Multicomponent Synthesis of Heterocycles

被引：43

作者：

Kruithof, Art ^{[1
]}

Ruijter, Eelco ^{[1
]}

Orru, Romano V. A. ^{[1
]}

机构：

[1] Vrije Univ Amsterdam, Dept Chem & Pharmaceut Sci, NL-1081 HV Amsterdam, Netherlands

来源：

CURRENT ORGANIC CHEMISTRY | 2011年 / 15卷 / 02期

关键词：

Combinatorial Chemistry; Heterocycles; Microwaves; Multicomponent reactions; One-Pot Reactions; Organic Synthesis; Reaction Efficiency; ONE-POT SYNTHESIS; SOLID-PHASE SYNTHESIS; EFFICIENT ONE-POT; SOLVENT-FREE CONDITIONS; 3-COMPONENT SYNTHESIS; ORGANIC-SYNTHESIS; CYCLOCONDENSATION REACTIONS; CHEMOSELECTIVE SYNTHESIS; COMBINATORIAL SYNTHESIS; COUPLING REACTIONS;

D O I：

10.2174/138527211793979817

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Multicomponent reactions are valuable tools for the generation of diverse heterocycles. As in many fields or organic chemistry, microwave irradiation is rapidly replacing conventional heating methods in multicomponent chemistry. In this review, we present an overview of recent applications of the use of microwaves in multicomponent heterocycle synthesis. Where possible, the yield and chemo-, regio- and stereoselectivity of microwave-assisted reactions are compared with those using conventional heating.

引用

页码：204 / 236

页数：33

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