Effects of the Dietary Approaches to Stop Hypertension (DASH) Eating Plan on Cardiovascular Risks Among Type 2 Diabetic Patients A randomized crossover clinical trial

被引:203
作者
Azadbakht, Leila [1 ,2 ]
Fard, Nafiseh Rashidi Pour [3 ]
Karimi, Majid [3 ]
Baghaei, Mohammad Hassan [3 ]
Surkan, Pamela J. [4 ]
Rahimi, Majid [3 ]
Esmaillzadeh, Ahmad [1 ,2 ]
Willett, Walter C. [5 ,6 ]
机构
[1] Isfahan Univ Med Sci, Food Secur Res Ctr, Esfahan, Iran
[2] Isfahan Univ Med Sci, Sch Publ Hlth, Dept Nutr, Esfahan, Iran
[3] Shaheed Motahari Hosp, Fooladshahr, Isfahan, Iran
[4] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Int Hlth, Baltimore, MD USA
[5] Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA
[6] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
关键词
BLOOD-PRESSURE; ASSOCIATION; PROTEIN; FAT;
D O I
10.2337/dc10-0676
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE- To determine the effects of the Dietary Approaches to Stop Hypertension (DASH) eating pattern on cardiometabolic risks in type 2 diabetic patients. RESEARCH DESIGN AND METHODS- A randomized crossover clinical trial was undertaken in 31 type 2 diabetic patients. For 8 weeks, participants were randomly assigned to a control diet or the DASH eating pattern. RESULTS- After following the DASH eating pattern, body weight (P = 0.007) and waist circumference (P = 0.002) reduced significantly. Fasting blood glucose levels and A1C decreased after adoption of the DASH diet (-29.4 +/- 6.3 mg/dl; P = 0.04 and -1.7 +/- 0.1%; P = 0.04, respectively). After the DASH diet, the mean change for HDL cholesterol levels was higher (4.3 +/- 0.9 mg/dl; P = 0.001) and LDL cholesterol was reduced (-17.2 +/- 3.5 mg/dl; P = 0.02). Additionally, DASH had beneficial effects on systolic (-13.6 +/- 3.5 vs. -3.1 +/- 2.7 mmHg; P = 0.02) and diastolic blood pressure (-9.5 +/- 2.6 vs. -0.7 +/- 3.3 mmHg; P = 0.04). CONCLUSIONS- Among diabetic patients, the DASH diet had beneficial effects on cardiometabolic risks.
引用
收藏
页码:55 / 57
页数:3
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