Enantioselective [2+2+2] Cycloaddition Reaction of Isocyanates and Allenes Catalyzed by Nickel

被引：52
作者：
Miura, Tomoya [1 ]
Morimoto, Masao [1 ]
Murakami, Masahiro [1 ]
机构：
[1] Kyoto Univ, Dept Synthet Chem & Biol Chem, Kyoto 6158510, Japan
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2010年 / 132卷 / 45期
关键词：
ALKENYL ISOCYANATES; ALKYNES; PYRIDONES; CONSTRUCTION; COMPLEXES;
D O I：
10.1021/ja105541r
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The enantioselective intermolecular [2 + 2 + 2] cycloaddition reaction of two molecules of isocyanate and one molecule of allene is catalyzed by a nickel(0)/(S,S)-i-Pr-FOXAP complex, providing an efficient access to enantiomerically enriched dihydropyrimidine-2,4-diones.
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收藏
页码：15836 / 15838
页数：3
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