Synthesis and anti-fungal properties of some simple cyclopentenones and derivatives

被引：12

作者：

Miller, JA ^{[1
]}

Pugh, AW ^{[1
]}

Ullah, GM ^{[1
]}

Welsh, GM ^{[1
]}

机构：

[1] Wellcome Res Labs, Dept Med Chem, Beckenham BR3 3BS, Kent, England

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 05期

关键词：

3+2] cycloaddition; allyl cations; sulphenyl cyclopentenones; anti-fungal activity;

D O I：

10.1016/S0040-4039(00)02110-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-Methylsulphenyl-2-phenylsulphenylethyne has been shown to be a precursor for either alpha -sulphenyl ketone or alpha -methylene ketone moieties in cyclopentenoids produced via [3+2] cycloaddition of an allyl cation. One of these ketones, the alpha -sulphenyl cyclopentenone 5, has been found to display potency against a range of fungi in vitro but its close analogues are largely inactive. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：955 / 959

页数：5

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