Listeria as a vaccine vector

被引：65

作者：

Bruhn, Kevin W.

Craft, Noah

Miller, Jeff F.

机构：

[1] Univ Calif Los Angeles, Med Ctr, Los Angeles Biomed Res Inst, Dept Med,Div Dermatol, Torrance, CA 90502 USA

[2] Univ Calif Los Angeles, Inst Mol Biol, David Geffen Sch Med, Dept Microbiol Immunol & Mol Genet, Los Angeles, CA 90095 USA

来源：

MICROBES AND INFECTION | 2007年 / 9卷 / 10期

关键词：

listeria monocytogenes; vaccine vector; cancer immunotherapy;

D O I：

10.1016/j.micinf.2007.05.010

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The immunostimulatory characteristics and intracellular niche of Listeria monocytogenes make it uniquely suitable for use as a live bacterial vaccine vector. Preclinical results supporting this idea, and current strategies to induce beneficial cell-mediated immunity to both infectious diseases and cancer with this vector, are discussed in this review. (C) 2007 Elsevier Masson SAS. All fights reserved.

引用

页码：1226 / 1235

页数：10

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