3D graphical representation of protein sequences and their statistical characterization

被引：50

作者：

el Maaty, Moheb I. Abo ^{[1
]}

Abo-Elkhier, Mervat M. ^{[1
]}

Abd Elwahaab, Marwa A. ^{[1
]}

机构：

[1] Mansoura Univ, Dept Engn Math & Phys, Fac Engn, Mansoura 35516, Egypt

来源：

PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS | 2010年 / 389卷 / 21期

关键词：

Protein sequence; Graphical representation; Numerical characterization; Similarity/dissimilarity analysis; Correlation and significance analysis; CHAOS GAME REPRESENTATION; DNA-SEQUENCES; SIMILARITY/DISSIMILARITY; DISTANCE;

D O I：

10.1016/j.physa.2010.06.031

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Based on three physicochemical properties of amino acid side chains, we proposed a novel unique 3D graphical representation of protein sequences. Then, we constructed two vectors of three components as mathematical objects to characterize protein sequences numerically. The similarity/dissimilarity analysis among nine ND5 protein sequences proved the utility of our approach. A correlation and significance analysis have been provided to compare our results and the sequence homology. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：4668 / 4676

页数：9