Influence of Melatonin-Correcting Drugs (Melaxen and Valdoxan) on the Levels of Superoxide Dismutase and Catalase Gene Transcription in Rats with Experimental Hyperthyroidism

被引：0

作者：

Popova, T. N. ^{[1
]}

Agarkov, A. A. ^{[1
]}

Gorbenko, M. V. ^{[1
]}

Popov, S. S. ^{[2
]}

Shul'gin, K. K. ^{[1
]}

机构：

[1] Voronezh State Univ, Voronezh 394036, Russia

[2] NN Burdenko Voronezh State Med Acad, Voronezh 394036, Russia

来源：

PHARMACEUTICAL CHEMISTRY JOURNAL | 2016年 / 50卷 / 03期

关键词：

gene-transcription level; melaxen; Valdoxan; superoxide dismutase; catalase; SACCHAROMYCES-CEREVISIAE; FREE-RADICALS; AGOMELATINE; METABOLISM; DISORDERS; SYSTEM;

D O I：

10.1007/s11094-016-1409-y

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The influence of the melatonin-correcting drugs melaxen and Valdoxan on the gene-transcription level of superoxide dismutase (SOD, EC 1.15.1.1) and catalase (EC 1.11.1.6) in liver and heart of rats with hyperthyroidism has been investigated. Administration of these drugs to rats with model pathology leads to changes in SOD and catalase expression in their tissues toward the control values.

引用

页码：127 / 130

页数：4

共 3 条

[1] Influence of Melatonin-Correcting Drugs (Melaxen and Valdoxan) on the Levels of Superoxide Dismutase and Catalase Gene Transcription in Rats with Experimental Hyperthyroidism
T. N. Popova
A. A. Agarkov
M. V. Gorbenko
S. S. Popov
K. K. Shul’gin
Pharmaceutical Chemistry Journal, 2016, 50 : 127 - 130
[2] Effects of Melaxen and Valdoxan on Superoxide Dismutase and Catalase Activities in Experimental Hyperthyroidism
M. V. Gorbenko
T. N. Popova
K. K. Shul’gin
S. S. Popov
Pharmaceutical Chemistry Journal, 2014, 47 : 577 - 580
[3] Effects of Melaxen and Valdoxan on Superoxide Dismutase and Catalase Activities in Experimental Hyperthyroidism
Gorbenko, M. V.
Popova, T. N.
Shul'gin, K. K.
Popov, S. S.
PHARMACEUTICAL CHEMISTRY JOURNAL, 2014, 47 (11) : 577 - 580

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