Linear IgA bullous dermatosis in a patient with renal cell carcinoma

被引:29
作者
Van der Waal, RIF
Van de Scheur, MR
Pas, HH
Jonkman, MF
Van Groeningen, CJ
Nieboer, C
Starink, TM
机构
[1] Univ Hosp Vrije Univ, Dept Dermatol, NL-1007 MB Amsterdam, Netherlands
[2] Univ Hosp Vrije Univ, Dept Med Oncol, NL-1007 MB Amsterdam, Netherlands
[3] Univ Groningen Hosp, Dept Dermatol, NL-9700 RB Groningen, Netherlands
关键词
linear IgA bullous dermatosis; paraneoplastic manifestation; renal cell carcinoma;
D O I
10.1046/j.1365-2133.2001.04148.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Linear IgA bullous dermatosis (LABD) is an autoimmune subepidermal bullous disease with heterogeneous clinical manifestations, characterized by linear deposition of IgA along the epidermal basement membrane zone. We report a patient with a metastasized renal cell carcinoma who developed an extensive blistering eruption. The lesions showed immunopathological findings characteristic of LABD. The patient showed a fair response to prednisolone and dapsone. Treatment to control the LABD was no longer required when interferon-alfa was started as palliative therapy for the metastasized renal cell carcinoma. The association of LABD and malignancies has been documented before and is not due to mere chance alone.
引用
收藏
页码:870 / 873
页数:4
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