Management of Motor Features in Advanced Parkinson Disease

被引:8
作者
Moore, Henry [1 ]
Shpiner, Danielle S. [1 ]
Luca, Corneliu C. [1 ]
机构
[1] Univ Miami, Miller Sch Med, Div Parkinson Dis & Movement Disorders, Dept Neurol, 1120 Northwest 14th St,1342, Miami, FL 33136 USA
关键词
Parkinson disease; Advanced Parkinson disease; Motor fluctuations; Dyskinesias; Deep brain stimulation; DEEP-BRAIN-STIMULATION; LEVODOPA-INDUCED DYSKINESIA; CARBIDOPA INTESTINAL GEL; DOUBLE-BLIND; APOMORPHINE; THERAPY; FLUCTUATIONS;
D O I
10.1016/j.cger.2019.09.010
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Advanced Parkinson disease (PD) is characterized by the presence of motor fluctuations becoming the focus of treatment, prominent postural instability, significant disability despite levodopa therapy, and the presence of symptoms refractory to levodopa therapy. In this article, the authors review the motor manifestations of patients with advanced PD, as well as the most common pharmacologic and nonpharmacologic available therapies.
引用
收藏
页码:43 / +
页数:11
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