A review of the clinical and diagnostic utility of laboratory tests for the detection of congenital thrombophilia

被引：32
作者：
Tripodi, A
机构：
[1] Univ Milan, Angelo Bianchi Bonomi Hemophilia & Thrombosis Ctr, Dept Internal Med, Milan, Italy
[2] Maggiore Hosp, IRCCS, Milan, Italy
来源：
SEMINARS IN THROMBOSIS AND HEMOSTASIS | 2005年 / 31卷 / 01期
关键词：
thrombophilia; screening; thrombosis; laboratory testing;
D O I：
10.1055/s-2005-863802
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Laboratory tests to detect congenital thrombophilia are frequently requested by clinicians. This review attempts to define (1) whether and to what extent laboratory testing may help clinicians make decisions on patient management, (2) the types of conditions to be investigated, and (3) the types of testing to be performed for each condition.
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页码：25 / 32
页数：8
相关论文
共 74 条
[1]  
ALHENCGELAS M, 1996, THROMB HAEMOSTASIS, V75, P971
[2]   NEW DIRECT ASSAY OF FREE PROTEIN-S ANTIGEN USING 2 DISTINCT MONOCLONAL-ANTIBODIES SPECIFIC FOR THE FREE-FORM [J].
AMIRAL, J ;
GROSLEY, B ;
BOYERNEUMANN, C ;
MARFAINGKOKA, A ;
PEYNAUDDEBAYLE, E ;
WOLF, M ;
MEYER, D .
BLOOD COAGULATION & FIBRINOLYSIS, 1994, 5 (02) :179-186
[3]  
Ariëns RAS, 1999, THROMB HAEMOSTASIS, V81, P203
[4]  
Bauer KA, 2001, THROMB HAEMOSTASIS, V85, P377
[5]   A factor V genetic component differing from factor V R506Q contributes to the activated protein C resistance phenotype [J].
Bernardi, F ;
Faioni, EM ;
Castoldi, E ;
Lunghi, B ;
Castaman, G ;
Sacchi, E ;
Mannucci, PM .
BLOOD, 1997, 90 (04) :1552-1557
[6]   MUTATION IN BLOOD-COAGULATION FACTOR-V ASSOCIATED WITH RESISTANCE TO ACTIVATED PROTEIN-C [J].
BERTINA, RM ;
KOELEMAN, BPC ;
KOSTER, T ;
ROSENDAAL, FR ;
DIRVEN, RJ ;
DERONDE, H ;
VANDERVELDEN, PA ;
REITSMA, PH .
NATURE, 1994, 369 (6475) :64-67
[7]   PROTEIN-CVERMONT - SYMPTOMATIC TYPE-II PROTEIN-C DEFICIENCY ASSOCIATED WITH 2 GLA DOMAIN MUTATIONS [J].
BOVILL, EG ;
TOMCZAK, JA ;
GRANT, B ;
BHUSHAN, F ;
PILLEMER, E ;
RAINVILLE, IR ;
LONG, GL .
BLOOD, 1992, 79 (06) :1456-1465
[8]  
Cattaneo M, 1999, THROMB HAEMOSTASIS, V81, P165
[9]   FAMILIAL THROMBOPHILIA DUE TO A PREVIOUSLY UNRECOGNIZED MECHANISM CHARACTERIZED BY POOR ANTICOAGULANT RESPONSE TO ACTIVATED PROTEIN-C - PREDICTION OF A COFACTOR TO ACTIVATED PROTEIN-C [J].
DAHLBACK, B ;
CARLSSON, M ;
SVENSSON, PJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (03) :1004-1008
[10]   A reduced sensitivity for activated protein C in the absence of factor V Leiden increases the risk of venous thrombosis [J].
de Visser, MCH ;
Rosendaal, FR ;
Bertina, RM .
BLOOD, 1999, 93 (04) :1271-1276
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