Current update on the visual outcome of optic pathway glioma associated with neurofibromatosis type-1

被引:6
作者
Zeid, Janice Lasky [1 ,2 ]
机构
[1] Ann & Robert H Lurie Childrens Hosp Chicago, Div Ophthalmol, Chicago, IL 60611 USA
[2] Northwestern Univ, Feinberg Sch Med, Dept Ophthalmol, Chicago, IL 60611 USA
关键词
optic pathway glioma; neurofibromatosis type 1; optic pathway tumor; diagnosis; treatment; FOLLOW-UP; CHILDREN; CARBOPLATIN; CHEMOTHERAPY; TUMORS; MANIFESTATIONS; VINCRISTINE;
D O I
10.3389/fsurg.2022.908573
中图分类号
R61 [外科手术学];
学科分类号
摘要
Purpose: Clinical and diagnostic evaluation in the follow-up of optic glioma patients with neurofibromatosis type 1 (NF-1) can be difficult. Determining whether and when to provide treatment is a significant challenge in best managing these patients. Update on current information and future directions in management is included in this review. Current Practice: NF-associated optic pathway gliomas (OPGs) present a significant management challenge with high stakes for visual outcomes. Monitoring vision and diagnostic tests are challenging in patients of a younger age. Regardless of whether few or many optic gliomas are encountered during clinical practice. Summary: This review of optic gliomas-NF1-associated gliomas includes the current approach and knowledge of OPG-NF1 and future directions in OPG-NF1 management. This includes the ongoing Multicenter Natural History Study and other clinical trials and outcomes in NF-1 patients with OPG.
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页数:5
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