Impact of Implementing the Paris System for Reporting Urinary Cytology: A Single-institutional Experience With Emphasis on Diagnostic Yield of High-grade Urothelial Carcinoma and Low-grade Urothelial Neoplasm

被引:6
作者
Koh, Hyun Hee [1 ]
Lee, Moon Jung [1 ]
Park, Noh Jin [1 ]
Kim, Hyun-Soo [1 ]
Oh, Young Lyun [1 ]
机构
[1] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pathol & Translat Genom, 81 Irwon Ro, Seoul 06351, South Korea
基金
新加坡国家研究基金会;
关键词
Urine; cytology; the Paris System; atypical urothelial cell; high-grade urothelial carcinoma; low-grade urothelial neoplasm; BLADDER-CANCER; ACCURACY; CRITERIA;
D O I
10.21873/anticanres.14334
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background/Aim: The Paris System (TPS) has recently been proposed as a method to standardize urinary cytology reporting. In this study, we evaluated the impact of implementing TPS compared to the traditional reporting system. Patients and Methods: In total, 299 urine samples were reclassified according to TPS. We examined correlations between cytological and histological diagnoses, and calculated probabilities for detecting high-grade urothelial carcinoma (HGUC). Results: TPS resulted in a decrease in the proportion of cases diagnosed as atypical urothelial cell (AUC) (43% to 31%). Among the AUC cases, the proportion of histologically confirmed HGUC cases rose (75% to 80%), as did the proportion of low-grade urothelial neoplasms (57% to 71%). All probabilities for detecting HGUC significantly increased using TPS. Conclusion: TPS improved the diagnostic yield of urinary cytology. The implementation of TPS is expected to be a major step towards standardizing urinary cytology reporting and providing clear information to clinicians.
引用
收藏
页码:3477 / 3484
页数:8
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