Mycoplasma pneumoniae pneumonia (MPP) is an acute respiratory tract infection caused by Mycoplasma pneumoniae. It is characterized by severe symptoms, long course of disease, many intrapulmonary complications, and poor therapeutic effect. In recent years, the incidence of Mycoplasma infection have been gradually rising trend, and the children's own immune system development is not mature, cases differences, children with mild can only show the upper respiratory tract infection, and critically ill children can lead to lung infection and even lead to multiple organ dysfunction, affect life and health of children. Soluble triggering receptors expressed on myeloid cell-1 (sTREM-1) is a subtype secreted by myeloid cell trigger receptor-1, which is released into blood in large amounts when the body is infected, and is a newly discovered inflammatory indicator in recent years. CXC chemokine 16 (CXCL-16) can recruit lymphocytes by chemotaxis through binding to its receptor CXCR6 to participate in the body's immune regulation. The purpose of this study was to investigate serum sTREM-1 and CXCL-16 levels in children with MPP and to analyze their correlation with the disease and diagnostic value. The results showed that the serum levels of sTREM-1 and CXCL-16 were increased in children with Mycoplasma. Serum levels of sTREM-1 and CXCL-16 were positively correlated with the severity of the disease. sTREM-1 combined with CXCL-16 has an important value in the diagnosis of children with MPP.
机构:
Hainan Women & Childrens Med Ctr, Dept Pharm, Haikou 570100, Hainan, Peoples R ChinaHainan Women & Childrens Med Ctr, Dept Pharm, Haikou 570100, Hainan, Peoples R China
Cao, Yingdong
Dong, Binbin
论文数: 0引用数: 0
h-index: 0
机构:
Fudan Univ, Huashan Hosp, Dept Pediat, Shanghai 200040, Peoples R ChinaHainan Women & Childrens Med Ctr, Dept Pharm, Haikou 570100, Hainan, Peoples R China
Dong, Binbin
Wang, Xuecheng
论文数: 0引用数: 0
h-index: 0
机构:
Wenzhou Med Univ, Dept Pediat, Dongyang Hosp, Dongyang 322100, Peoples R ChinaHainan Women & Childrens Med Ctr, Dept Pharm, Haikou 570100, Hainan, Peoples R China
Wang, Xuecheng
Wang, Chunrong
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai Jiading Hosp Tradit Chinese Med, Dept Pediat, Shanghai 201899, Peoples R ChinaHainan Women & Childrens Med Ctr, Dept Pharm, Haikou 570100, Hainan, Peoples R China
机构:
Bursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, TurkiyeBursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, Turkiye
Cakir, Salih cagri
Dorum, Bayram Ali
论文数: 0引用数: 0
h-index: 0
机构:
Bursa City Hosp, Dept Pediat, Div Neonatol, TR-16110 Bursa, TurkiyeBursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, Turkiye
Dorum, Bayram Ali
Ozkan, Hilal
论文数: 0引用数: 0
h-index: 0
机构:
Bursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, TurkiyeBursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, Turkiye
Ozkan, Hilal
Koksal, Nilgun
论文数: 0引用数: 0
h-index: 0
机构:
Bursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, TurkiyeBursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, Turkiye
Koksal, Nilgun
Kocael, Fatma
论文数: 0引用数: 0
h-index: 0
机构:
Bursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, TurkiyeBursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, Turkiye
Kocael, Fatma
Budak, Ferah
论文数: 0引用数: 0
h-index: 0
机构:
Bursa Uludag Univ, Fac Med, Dept Immunol, TR-16059 Bursa, TurkiyeBursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, Turkiye
Budak, Ferah
Hacimustafaoglu, Mustafa
论文数: 0引用数: 0
h-index: 0
机构:
Bursa Uludag Univ, Fac Med, Dept Pediat, Div Pediat Infect Dis, TR-16059 Bursa, TurkiyeBursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, Turkiye
Hacimustafaoglu, Mustafa
Celebi, Solmaz
论文数: 0引用数: 0
h-index: 0
机构:
Bursa Uludag Univ, Fac Med, Dept Pediat, Div Pediat Infect Dis, TR-16059 Bursa, TurkiyeBursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, Turkiye
Celebi, Solmaz
Kizmaz, Muhammed Ali
论文数: 0引用数: 0
h-index: 0
机构:
Bursa Uludag Univ, Fac Med, Dept Immunol, TR-16059 Bursa, TurkiyeBursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, Turkiye
Kizmaz, Muhammed Ali
Yildirim, Cansu Sivrikaya
论文数: 0引用数: 0
h-index: 0
机构:
Bursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, TurkiyeBursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, Turkiye
Yildirim, Cansu Sivrikaya
Elmas, Kevser Ustun
论文数: 0引用数: 0
h-index: 0
机构:
Bursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, TurkiyeBursa Uludag Univ, Fac Med, Dept Pediat, Div Neonatol, TR-16059 Bursa, Turkiye