A novel electrosynthesized polymer applied to molecular imprinting technology

被引：51

作者：

Gong, JL ^{[1
]}

Gong, FC ^{[1
]}

Zeng, GM ^{[1
]}

Shen, GL ^{[1
]}

Yu, RQ ^{[1
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab ChemoBiosensing & Chemometr, Changsha 410082, Peoples R China

来源：

TALANTA | 2003年 / 61卷 / 04期

基金：

中国国家自然科学基金;

关键词：

2-mercaptobenzimidazole; molecular imprinting; electropolymerization; cholesterol;

D O I：

10.1016/S0039-9140(03)00317-5

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Poly(2-macaptobenzimidazole) (PMBI) films are prepared at the gold electrode surface by electropolymerization using imprinting technology and the target analyte cholesterol is used as the template. A cholesterol-selective sensor based on PMBI film was employed in conjunction with differential pulse voltammetry (DPV) and ferricyanide as mediator. Concentration of cholesterol up to 100 muM could be detected with a linear determination range up to 20 muM and a detection limit of 0.7 muM. The molecular imprinting approach offers a relatively nice selectivity for the sensor toward cholesterol with respect to common coexisting substances. The method is simple and the stability of the electrode prepared is satisfactory. The results of this research show the feasibility of using molecular imprinting methodology for preparing sensing devices for analytes that are electrochemically inactive. (C) 2003 Elsevier B.V. All rights reserved.

引用

页码：447 / 453

页数：7

共 18 条

[1] Electrosynthesis of adherent poly(2-mercaptobenzimidazole) films on brass prepared in nonaqueous solvents [J].